Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

Background Sleep phenotypes have been reported to be associated with cognitive ageing
outcomes. However, there is limited research using genetic variants as proxies for sleep …

Background Genome-wide association studies (GWAS) for obstructive sleep apnoea (OSA)
are limited due to the underdiagnosis of OSA, leading to misclassification of OSA, which …

Abstract Study Objectives Growing evidence linked inflammation with sleep. This study
aimed to evaluate the associations and causal effects of sleep traits including insomnia …

Objectives: Correlations between obstructive sleep apnea (OSA) and gastroesophageal
reflux disease (GERD) have been detected in previous observational studies. However, this …

Abstract Sleep Disordered Breathing (SDB) is a common disease associated with increased
risk for cardiometabolic, cardiovascular, and cognitive diseases. How SDB affects the …

Obstructive sleep apnea (OSA) and cardiovascular co‐morbidities have a mutually
reinforcing effect, but existing studies have focussed only on the improvement of the …

Purpose The aim of our study is to estimate the associations and causalities of glucose
metabolism traits of fasting blood glucose (FBG), fasting insulin (FINS), glycosylated …

Objectives A multitude of physical and mental challenges are being faced in the population
with Co-morbid Insomnia and Sleep Apnea (COMISA). Unfortunately, research about clinical …

Insulin resistance (IR) and beta cell dysfunction are the major drivers of type 2 diabetes
(T2D). Genome-Wide Association Studies (GWAS) on IR have been predominantly …