[HTML][HTML] Quercetin for managing type 2 diabetes and its complications, an insight into multitarget therapy

R Dhanya - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Background Quercetin, a bioflavonoid abundant in grapefruit, onion, berries, etc., has vast
therapeutic potential, especially against Type 2 diabetes and its complications. Quercetin …

[HTML][HTML] In vitro and in vivo evidence that quercetin protects against diabetes and its complications: A systematic review of the literature

GJ Shi, Y Li, QH Cao, HX Wu, XY Tang, XH Gao… - Biomedicine & …, 2019 - Elsevier
Quercetin, a typical flavonoid, possesses diverse biochemical and physiological actions,
including antiplatelet, estrogenic, and anti-inflammatory properties. This review mainly …

[HTML][HTML] Quercetin alleviates acute kidney injury by inhibiting ferroptosis

Y Wang, F Quan, Q Cao, Y Lin, C Yue, R Bi… - Journal of advanced …, 2021 - Elsevier
Introduction Ferroptosis is an iron-dependent regulated necrosis and has been proven to
contribute to the progress of acute kidney injury (AKI). Quercetin (QCT), a natural flavonoid …

Potential pharmaceutical applications of quercetin in cardiovascular diseases

P Papakyriakopoulou, N Velidakis, E Khattab… - Pharmaceuticals, 2022 - mdpi.com
Quercetin, as a member of flavonoids, has emerged as a potential therapeutic agent in
cardiovascular diseases (CVDs) in recent decades. In this comprehensive literature review …

Therapeutic effects and safe uses of plant-derived polyphenolic compounds in cardiovascular diseases: a review

BS Alotaibi, M Ijaz, M Buabeid, ZJ Kharaba… - Drug design …, 2021 - Taylor & Francis
Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

The effect of hesperidin and quercetin on oxidative stress, NF-κB and SIRT1 levels in a STZ-induced experimental diabetes model

H Iskender, E Dokumacioglu, TM Sen, I Ince… - Biomedicine & …, 2017 - Elsevier
Objective The aim of this study is to investigate the roles of SIRT1 and NF-κB in the
pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the …

The effect of quercetin on diabetic nephropathy (DN): a systematic review and meta-analysis of animal studies

T Hu, J Yue, Q Tang, KW Cheng, F Chen, M Peng… - Food & Function, 2022 - pubs.rsc.org
Quercetin, a flavonoid possessing numerous biological activities, is reported to improve
renal injury in diabetic animals. Here, the aim of this systematic review and meta-analysis is …

Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

YQ Chen, HY Chen, QQ Tang, YF Li, XS Liu… - Frontiers in …, 2022 - frontiersin.org
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but
effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely …

Advance on the absorption, metabolism, and efficacy exertion of quercetin and its important derivatives: absorption, metabolism and function of quercetin

Y Hai, Y Zhang, Y Liang, X Ma, X Qi, J Xiao… - Food …, 2020 - Wiley Online Library
Quercetin, a dietary flavonol, has been used as potential ingredient in food supplements to
promote health. Its health effects are closely related to its bioavailability and further depend …

Quercetin, a plant flavonol attenuates diabetic complications, renal tissue damage, renal oxidative stress and inflammation in streptozotocin-induced diabetic rats

AH Rahmani, MA Alsahli, AA Khan, SA Almatroodi - Metabolites, 2023 - mdpi.com
Diabetes mellitus is a metabolic syndrome characterized by increased glucose levels,
oxidative stress, hyperlipidemia, and frequently decreased insulin levels. The current …