Endothelial progenitor cells (EPCs) play an important role in repairing damaged blood
vessels and promoting neovascularization. However, the specific mechanism of EPCs …

Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Background Distraction osteogenesis (DO) is a widely used bone regenerative technique.
However, the DO process is slow, and the consolidation phase is long. Therefore, it is of …

Diabetes mellitus (DM) constitutes a chronic metabolic disease characterized by elevated
levels of blood glucose which can also lead to the so-called diabetic vascular complications …

Background Critical limb-threatening ischemia (CLTI) constitutes the most severe
manifestation of peripheral artery disease, usually induced by atherosclerosis. CLTI patients …

Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic
agents for wound repair, recapitulating the biological effects of parent cells while mitigating …

Cardiovascular diseases remain the leading cause of death worldwide, mainly triggered by
the formation of atherosclerotic plaques that reduce blood flow. Angiogenic cell therapy …

Background The transplantation of endothelial progenitor cells (EPCs) has been shown to
reduce neointimal hyperplasia following arterial injury. However, the efficacy of this …

Endothelial progenitor cells (EPCs) are involved in vascular repair and modulate properties
of smooth muscle cells (SMCs) relevant for their contribution to neointima formation …

Aging is a major risk factor of atherosclerosis through different complex pathways including
replicative cellular senescence and age-related clonal hematopoiesis. In addition to aging …