Melanoma is the most aggressive and deadliest type of skin cancer. In the last 10 years,
immune checkpoint blockades (ICBs) including PD-1/PD-L1 and CTLA-4 inhibitor has been …

The coagulation and immune systems, two vital systems in the human body, share intimate
connections that fundamentally determine patient health. These systems work together …

Ezrin is the cytoskeletal organizer and functions in the modulation of membrane–
cytoskeleton interaction, maintenance of cell shape and structure, and regulation of cell–cell …

Simple Summary International standards recommend booster immunization against SARS-
CoV-2 in advanced cancer patients undergoing active treatment. Little is known about the …

Melanoma is among the most lethal forms of cancer, accounting for 80% of deaths despite
comprising just 5% of skin cancer cases. Treatment options remain limited due to the genetic …

Simple Summary Glioblastoma (GBM) is an aggressive brain tumor that is heterogenous at
the cellular and molecular levels. It deftly invades the brain parenchyma making it …

Simple Summary Precision oncology is emerging as a viable option to improve survival in
patients who fail to remain disease-free even after the employment of currently available …

Glioblastoma multiform (GBM) is the most prevalent CNS (central nervous system) tumor in
adults, with an average survival length shorter than 2 years and rare metastasis to organs …

Organotropism has been known since 1889, yet this vital component of metastasis has
predominantly stayed elusive. This mini-review gives an overview of the current …

Immunotherapy has been a research hotspot due to its low side effects, long-lasting efficacy,
and wide anti-tumor spectrum. Recently, NK cell-based immunotherapy has gained broad …