Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid
peroxidation and GSH depletion mediated by iron metabolism and is morphologically …

Microglia are the resident innate immune cells in the brain with a major role in orchestrating
immune responses. They also provide a frontline of host defense in the central nervous …

Ferroptosis and neuroinflammation play crucial roles in Alzheimer's disease (AD)
pathophysiology. Forsythoside A (FA), the main constituent of Forsythia suspensa (Thunb.) …

Parkinson's disease (PD) is a slowly progressive neurodegenerative disease characterized
by α-synuclein aggregation and dopaminergic neuronal death. Recent evidence suggests …

Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …

The pathogenesis and clinical heterogeneity of Parkinson's disease (PD) have been
evaluated from molecular, pathophysiological, and clinical perspectives. High-throughput …

Abstracts Ethnopharmacological relevance Saikosaponins B2 (SSB2) is one of the main
active components isolated from Radix Bupleuri (Bupleurum chinense DC.), a herb widely …

In recent years, three emerging cell deaths, ferroptosis, necroptosis and pyroptosis, have
gradually attracted everyone's attention, and they also play an important role in the …