[HTML][HTML] Luteolin, a flavonoid, as an anticancer agent: A review

M Imran, A Rauf, T Abu-Izneid, M Nadeem… - Biomedicine & …, 2019 - Elsevier
Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-
cancer compounds. Luteolin (3, 4, 5, 7-tetrahydroxy flavone) is a flavonoid found in different …

Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma

D Kempuraj, R Thangavel, DD Kempuraj… - Biofactors, 2021 - Wiley Online Library
Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative
disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells …

Dietary anti-aging polyphenols and potential mechanisms

J Luo, H Si, Z Jia, D Liu - Antioxidants, 2021 - mdpi.com
For years, the consumption of a diet rich in fruits and vegetables has been considered
healthy, increasing longevity, and decreasing morbidities. With the assistance of basic …

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

M Zhang, C An, Y Gao, RK Leak, J Chen… - Progress in …, 2013 - Elsevier
Phase II metabolic enzymes are a battery of critical proteins that detoxify xenobiotics by
increasing their hydrophilicity and enhancing their disposal. These enzymes have long been …

Linking oxidative stress and proteinopathy in Alzheimer's disease

C Sharma, SR Kim - Antioxidants, 2021 - mdpi.com
Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …

Pharmacological modulation of Nrf2/HO-1 signaling pathway as a therapeutic target of Parkinson's disease

Y Wang, L Gao, J Chen, Q Li, L Huo, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a complex neurodegenerative disorder featuring both motor and
nonmotor symptoms associated with a progressive loss of dopaminergic neurons in the …

Luteolin, a flavonoid with potential for cancer prevention and therapy

Y Lin, R Shi, X Wang, HM Shen - Current cancer drug targets, 2008 - ingentaconnect.com
Luteolin, 3', 4', 5, 7-tetrahydroxyflavone, is a common flavonoid that exists in many types of
plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been …

Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

SA Ganai, FA Sheikh, ZA Baba, MA Mir… - Phytotherapy …, 2021 - Wiley Online Library
Various signaling mechanisms contribute significantly to the development of multiple
cancers. Small molecules with the potential of influencing a wide variety of molecular targets …

Distribution and biological activities of the flavonoid luteolin

M López-Lázaro - Mini reviews in medicinal chemistry, 2009 - ingentaconnect.com
Epidemiological evidence suggests that flavonoids may play an important role in the
decreased risk of chronic diseases associated with a diet rich in plant-derived foods …

Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ142-Induced Alzheimer's Disease

S Ahmad, MH Jo, M Ikram, A Khan, MO Kim - International Journal of …, 2021 - mdpi.com
The current study was undertaken to unveil the protective effects of Luteolin, a natural
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …