Increased interleukin-6 levels associated with malaria infection and disease severity: a systematic review and meta-analysis

P Wilairatana, W Mala, GDJ Milanez, FR Masangkay… - Scientific Reports, 2022 - nature.com
Abstract Interleukin-6 (IL-6) is generated by immune cells during infection with malaria
parasites and they are associated with the immunopathogenesis of malaria. The present …

Association of cerebral malaria and TNF-α levels: a systematic review

L Leão, B Puty, MF Dolabela, MM Povoa… - BMC infectious …, 2020 - Springer
Background Cerebral malaria is the most severe form of infection with Plasmodium
falciparum characterized by a highly inflammatory response. This systematic review aimed …

Association of ABO blood group and Plasmodium falciparum malaria in Dore Bafeno Area, Southern Ethiopia

T Zerihun, A Degarege, B Erko - Asian Pacific Journal of Tropical …, 2011 - Elsevier
Objective To assess the distribution of ABO blood group and their relationship with
Plasmodium falciparum (P. falciparum) malaria among febrile outpatients who sought …

Increased interferon-γ levels and risk of severe malaria: a meta-analysis

A Mahittikorn, W Mala, FR Masangkay, KU Kotepui… - Scientific reports, 2022 - nature.com
Interferon (IFN)-γ contributes to the pathogenesis of severe malaria; however, its mechanism
remains unclear. Herein, differences in IFN-γ levels between patients with severe and …

Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in …

H Onohuean, AI Alagbonsi, IM Usman… - Journal of evidence …, 2021 - journals.sagepub.com
Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the
treatment of malaria and have been experimentally shown to have an anti-plasmodial effect …

Tumour necrosis factor alpha promoter polymorphism, TNF-238 is associated with severe clinical outcome of falciparum malaria in Ibadan southwest Nigeria

SA Olaniyan, OK Amodu, AA Bakare… - Acta tropica, 2016 - Elsevier
Tumour necrosis factor (TNF)–α has been shown to play an important role in the
pathogenesis of falciparum malaria. Two TNF promoter polymorphisms, TNF-308 and TNF …

Malaria parasite carbonic anhydrase: inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential

SR Krungkrai, J Krungkrai - Asian Pacific journal of tropical biomedicine, 2011 - Elsevier
Plasmodium falciparum (P. falciparum) is responsible for the majority of life-threatening
cases of human malaria, causing 1.5–2.7 million annual deaths. The global emergence of …

Interleukin-5 levels in relation to malaria severity: a systematic review

M Kotepui, T Duangchan, A Mahittikorn, C Mekhora… - Malaria Journal, 2023 - Springer
Background The role of cytokines such as interleukin-5 (IL-5) in the pathogenesis of malaria
remains unclear. This systematic review sought to synthesize variations in IL-5 levels …

A systematic review and meta-analysis of blood interleukin-4 levels concerning malaria infection and severity

KU Kotepui, P Thirarattanasunthon, P Rattaprasert… - Malaria Journal, 2022 - Springer
Abstract Background Interleukin (IL)-4 had been linked to malaria severity, but the findings
are controversial, and the evidence is inconsistent and imprecise. In the current …

[HTML][HTML] Role of cytokines in immunomodulation during malaria clearance

EI Obeagu - Annals of Medicine and Surgery, 2024 - journals.lww.com
Malaria remains a significant global health challenge, demanding a deeper understanding
of host immune responses for effective clearance of the parasitic infection. Cytokines, as …