Genetic alterations in salivary gland cancers

LX Yin, PK Ha - Cancer, 2016 - Wiley Online Library
Salivary gland cancers are an incredibly heterogeneous group of tumors that include 24
histologically distinct tumor types. The use of new genetic methods has paved the way for …

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

JP Lopez, E Brivio, A Santambrogio, C De Donno… - Science …, 2021 - science.org
Chronic activation and dysregulation of the neuroendocrine stress response have severe
physiological and psychological consequences, including the development of metabolic and …

Suprabasin—A review

M Pribyl, Z Hodny, I Kubikova - Genes, 2021 - mdpi.com
Among the~ 22,000 human genes, very few remain that have unknown functions. One such
example is suprabasin (SBSN). Originally described as a component of the cornified …

SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling

Z Zhou, Z Zhang, H Chen, W Bao, X Kuang… - British Journal of …, 2022 - nature.com
Background Patients with metastatic bladder cancer have very poor prognosis and
predictive biomarkers are urgently needed for early clinical detection and intervention. In this …

Porphyromonas gingivalis promotes immunoevasion of oral cancer by protecting cancer from macrophage attack

S Liu, X Zhou, X Peng, M Li, B Ren… - The Journal of …, 2020 - journals.aai.org
SL contributed to conception, design, acquisition, analysis, interpretation of data, and drafted
and critically revised the manuscript. XZ contributed to conception and critically revised the …

Novel insight into mutational landscape of head and neck squamous cell carcinoma

DA Gaykalova, E Mambo, A Choudhary, J Houghton… - PloS one, 2014 - journals.plos.org
Development of head and neck squamous cell carcinoma (HNSCC) is characterized by
accumulation of mutations in several oncogenes and tumor suppressor genes. We have …

Correlation of gene methylation in surgical margin imprints with locoregional recurrence in head and neck squamous cell carcinoma

M Hayashi, G Wu, JL Roh, X Chang, X Li, J Ahn… - Cancer, 2015 - Wiley Online Library
BACKGROUND Securing negative surgical margins is a critical goal for head and neck
surgery. Local recurrence develops even in some patients who have histologically negative …

Suprabasin as a novel tumor endothelial cell marker

MT Alam, H Nagao‐Kitamoto, N Ohga… - Cancer …, 2014 - Wiley Online Library
Recent studies have reported that stromal cells contribute to tumor progression. We
previously demonstrated that tumor endothelial cells (TEC) characteristics were different …

Overexpression of suprabasin is associated with proliferation and tumorigenicity of esophageal squamous cell carcinoma

J Zhu, G Wu, Q Li, H Gong, J Song, L Cao, S Wu… - Scientific reports, 2016 - nature.com
Suprabasin is a recently identified oncoprotein that is upregulated in multiple cancers.
However, the clinical significance and biological role of suprabasin in human esophageal …

Outlier analysis defines zinc finger gene family DNA methylation in tumors and saliva of head and neck cancer patients

DA Gaykalova, R Vatapalli, Y Wei, HL Tsai, H Wang… - PloS one, 2015 - journals.plos.org
Head and Neck Squamous Cell Carcinoma (HNSCC) is the fifth most common cancer,
annually affecting over half a million people worldwide. Presently, there are no accepted …