Phytic acid: Properties and potential applications in dentistry

M Nassar, R Nassar, H Maki, A Al-Yagoob… - Frontiers in …, 2021 - frontiersin.org
Inositol hexaphosphate (IP6) is the most abundant inositol phosphate in nature and an
essential molecule for different biological functions. IP6 has a unique structure granting it …

Matrix metalloproteinases in dentin: Assessing their presence, activity, and inhibitors–a review of current trends

L Anumula, S Ramesh, VSK Kolaparthi - Dental Materials, 2024 - Elsevier
Introduction Dentin integrity is a critical aspect of tooth structure, with matrix
metalloproteinases (MMPs) playing a crucial role in dentinogenesis, caries formation, and …

Antimicrobial activity of phytic acid: An emerging agent in endodontics

R Nassar, M Nassar, ME Vianna, N Naidoo… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Phytic acid (IP6) is a promising and emerging agent, and because of its unique
structure and distinctive properties, it lends itself to several applications in dentistry …

Effect of phytic acid on dentinal collagen solubilization and its binding and debinding potentials to dentin

D Forgione, M Nassar, R Seseogullari-Dirihan… - Journal of Dentistry, 2023 - Elsevier
Objectives To study phytic acid (IP6) effect on collagen solubilization by assessing
hydroxyproline (HYP) release, evaluate its binding to demineralized (DD) and mineralized …

[HTML][HTML] Effect of inositol hexaphosphate acid versus polyacrylic acid on dentin properties and adhesion of a self-adhesive restorative material to dentin

MM Awad, F Alhalabi, F Arishi, A Ateen… - International Journal of …, 2024 - Elsevier
Objective This study evaluated the effect of 2% inositol hexaphosphate (IP6) and 10%
polyacrylic acid (PAA) on dentin surface micromorphology, matrix/mineral ratio …

Application of inositol hexaphosphate and inositol in dental medicine: an overview

A Druzijanic, M Kovic, M Roguljic, L Cigic… - Biomolecules, 2023 - mdpi.com
Phosphorylated inositol hexaphosphate (IP6) is a naturally occurring carbohydrate, and its
parent compound, myoinositol (Ins), is abundantly present in plants, particularly in certain …

The effect of different conditioning agents on dentin roughness and collagen structure

K Anastasiadis, M Nassar - Journal of Dentistry, 2024 - Elsevier
Objectives To assess the impact of various organic and inorganic acids on the roughness,
demineralization, and collagen secondary structures of human dentin and to compare these …

Impact of cathepsin K-induced proteoglycans degradation on dentin collagen

N Jiang, Y Chen, X Lin, H Yu - Archives of Oral Biology, 2025 - Elsevier
Objectives This study aimed to investigate the effects of cathepsin K (catK) on proteoglycans
(PGs) and the subsequent impacts on dentin collagen degradation. Materials and Methods …

Effect of Phytic Acid Addition on the Structure of Collagen-Hyaluronic Acid Composite Gel

Y Nashchekina, E Guryanov, A Lihachev, G Vaganov… - Gels, 2023 - mdpi.com
Composite collagen gels with hyaluronic acid are developed tissue-engineered structures
for filling and regeneration of defects in various organs and tissues. For the first time, phytic …

Resin-based cement applied to enamel and dentin pre-treated with phytic acid: An in vitro study

M Nassar, MS Islam, SA AC, HM El-Damanhoury… - Applied Sciences, 2021 - mdpi.com
Phytic acid (IP6) has the ability to etch tooth structure due to its acidity and chelating
properties. This study aimed to evaluate the micro-tensile bond strength (μTBS) of resin …