Oral microbiome and SARS-CoV-2: beware of lung co-infection

L Bao, C Zhang, J Dong, L Zhao, Y Li… - Frontiers in microbiology, 2020 - frontiersin.org
The new coronavirus SARS-CoV-2, the cause of COVID-19, has become a public health
emergency of global concern. Like the SARS and influenza pandemics, there have been a …

Porphyromonas gingivalis and Its Systemic Impact: Current Status

F Mei, M Xie, X Huang, Y Long, X Lu, X Wang, L Chen - Pathogens, 2020 - mdpi.com
The relationship between periodontitis and systemic diseases, notably including
atherosclerosis and diabetes, has been studied for several years. Porphyromonas …

Aspiration of periodontopathic bacteria due to poor oral hygiene potentially contributes to the aggravation of COVID-19

Y Takahashi, N Watanabe, N Kamio… - Journal of oral …, 2021 - jstage.jst.go.jp
Coronavirus infectious disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) was declared a pandemic in March 2020 by the …

The type IX secretion system (T9SS): highlights and recent insights into its structure and function

AM Lasica, M Ksiazek, M Madej… - Frontiers in cellular and …, 2017 - frontiersin.org
Protein secretion systems are vital for prokaryotic life, as they enable bacteria to acquire
nutrients, communicate with other species, defend against biological and chemical agents …

One-step hydrothermal synthesis of photoluminescent carbon nanodots with selective antibacterial activity against Porphyromonas gingivalis

J Liu, S Lu, Q Tang, K Zhang, W Yu, H Sun, B Yang - Nanoscale, 2017 - pubs.rsc.org
Carbon dots (CDs) with high quantum yield (QY), low toxicity and good biocompatibility are
the major quests of biomedical research. In this paper, we develop a green, simple …

Severe COVID-19 lung infection in older people and periodontitis

R Aquino-Martinez, S Hernández-Vigueras - Journal of Clinical Medicine, 2021 - mdpi.com
Periodontal bacteria dissemination into the lower respiratory tract may create favorable
conditions for severe COVID-19 lung infection. Once lung tissues are colonized, cells that …

Novel insight into the mechanisms of the bidirectional relationship between diabetes and periodontitis

F Barutta, S Bellini, M Durazzo, G Gruden - Biomedicines, 2022 - mdpi.com
Periodontitis and diabetes are two major global health problems despite their prevalence
being significantly underreported and underestimated. Both epidemiological and …

Gut-brain pathogenesis of post-acute COVID-19 neurocognitive symptoms

AM Plummer, YL Matos, HC Lin, SG Ryman… - Frontiers in …, 2023 - frontiersin.org
Approximately one third of non-hospitalized coronavirus disease of 2019 (COVID-19)
patients report chronic symptoms after recovering from the acute stage of severe acute …

Ingestion of Porphyromonas gingivalis exacerbates colitis via intestinal epithelial barrier disruption in mice

T Tsuzuno, N Takahashi… - Journal of …, 2021 - Wiley Online Library
Objective This study aimed to evaluate the effects of ingested periodontal pathogens on
experimental colitis in mice and to elucidate its underlying mechanisms. Background …

Periodontopathogens Porphyromonas gingivalis and Fusobacterium nucleatum and Their Roles in the Progression of Respiratory Diseases

T Shi, J Wang, J Dong, P Hu, Q Guo - Pathogens, 2023 - mdpi.com
The intricate interplay between oral microbiota and the human host extends beyond the
confines of the oral cavity, profoundly impacting the general health status. Both periodontal …