Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Allergic rhinitis (AR) is a global health problem with increasing prevalence and association
with an enormous medical and socioeconomic burden. New recognition of immune cells …

An updated edition of the International Consensus Statement on Allergy and Rhinology:
Allergic Rhinitis (ICAR: AR) has recently been published. This consensus document, which …

Allergen-specific immunotherapy (AIT) is presumed to modulate the natural course of
allergic disease by inducing immune tolerance. However, conventional AITs, such as …

Injecting allergen directly into a lymph node strengthens the protective immune response.
ILIT is safe and induces desensitization and very likely also induces tolerance. Compliance …

Immunoglobulin E (IgE)–mediated allergic diseases, including eczema, atopic dermatitis
(AD), and allergic rhinitis (AR), have increased prevalence in recent decades. Recent …

Introduction Allergy, the immunological hypersensitivity to innocuous environmental
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …

Background. Intralymphatic immunotherapy (ILIT) is short‐course administration of allergen‐
specific immunotherapy (AIT). This study is aimed at assessing the clinical efficacy and …

Lymph nodes (LNs) occupy a critical position in initiating and augmenting immune
responses, both spatially and functionally. In cancer immunotherapy, tumor-specific …

Background In 2002-2005, we conducted a phase I/II clinical trial where a new allergy
immunotherapy (AIT) route was introduced: intralymphatic immunotherapy (ILIT). Ultrasound …