Rheumatoid arthritis (RA) is a chronic autoimmune disease that endangers the health of
approximately 1% of the global population. Current RA medications on the market mainly …

Bone and immune systems mutually influence each other by sharing a variety of regulatory
molecules and the tissue microenvironment. The interdisciplinary research field …

Extracts from Taiwan's traditional medicinal mushroom, Antrodia cinnamomea, exhibit anti-
inflammatory activities in cellular and preclinical studies. However, this paper is the first to …

Purpose Network pharmacology is considered to be the next-generation drug development
model that uses bioinformatics to predict and identify multiple drug targets and interactions …

Systemic lupus erythematosus (SLE) is an inflammatory disorder related to immunity
dysfunction. The Th1 cell family including Th1 cells, transcription factor T-bet, and related …

Biological agents that neutralize the activity of pro-inflammatory cytokines are revolutionizing
the treatment of inflammatory conditions. However, the antibodies (Abs) short half-life and off …

The treatment of autoimmune and inflammatory diseases often requires targeting multiple
pathogenic pathways. KYS202004A is a novel bispecific fusion protein designed to …

As a means of communication between immune cells and non-immune cells, Interleukins
(ILs) has the main functions of stimulating the proliferation and activation of inflammatory …

In recent decades, biological agents such as tumor necrosis factor-α (TNF-α) inhibitors, have
revolutionized the treatment of psoriasis. However, inhibition of a single cytokine may not …

The inhibition of tumor necrosis factor (TNF) through the use of either antibodies or soluble
receptors is a highly effective strategy for the clinical control of chronic inflammatory …