Mucosal administration, and specifically nasal route, constitutes an alternative and
promising strategy for drug and vaccine delivery. Mucosal routes have several advantages …

The development of new adjuvants for human vaccines has become an expanding field of
research in the last thirty years, for generating stronger vaccines capable of inducing …

Virus-like particles (VLPs) are self-assembled structures derived from viral antigens that
mimic the native architecture of viruses but lack the viral genome. VLPs have emerged as a …

Recombinant virus-like particle-based vaccines are composed of viral structural proteins
and mimic authentic native viruses but are devoid of viral genetic materials. They are the …

Virus-like particles (VLPs) have been extensively explored as nanoparticle vehicles for
many applications in biotechnology (eg, vaccines, drug delivery, imaging agents …

Context Current drugs for chronic hepatitis B therapy have a poor efficacy in terms of post-
treatment sustained viral suppression and generate important side effects during and after …

Induction of curative immune responses by therapeutic vaccination in chronic viral infections
such as chronic hepatitis B (CHB) is expected to be facilitated by reduction of viral load by …

The treatment of chronic hepatitis B virus (HBV) infection has greatly improved over the last
10years, but alternative treatments are still needed. Therapeutic vaccination is a promising …

Background Hepatitis B virus infection remains an important global health concern despite
the availability of safe and effective prophylactic vaccines. Limitations to these vaccines …

Vaccines are one of the most effective medical interventions to combat newly emerging and
re-emerging diseases. Prophylactic vaccines against rabies, measles, etc., have excellent …