Nonsense-mediated mRNA decay, a finely regulated mechanism
F Lejeune - Biomedicines, 2022 - mdpi.com
Nonsense-mediated mRNA decay (NMD) is both a mechanism for rapidly eliminating
mRNAs carrying a premature termination codon and a pathway that regulates many genes …
mRNAs carrying a premature termination codon and a pathway that regulates many genes …
No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors
J Mailliot, M Vivoli-Vega, C Schaffitzel - Biochemical Journal, 2022 - portlandpress.com
Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance
pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to …
pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to …
Nonsense-mediated mRNA decay factor functions in human health and disease
L Sun, J Mailliot, C Schaffitzel - Biomedicines, 2023 - mdpi.com
Nonsense-mediated mRNA decay (NMD) is a cellular surveillance mechanism that
degrades mRNAs with a premature stop codon, avoiding the synthesis of C-terminally …
degrades mRNAs with a premature stop codon, avoiding the synthesis of C-terminally …
Messenger RNA Surveillance: Current Understanding, Regulatory Mechanisms, and Future Implications
R Das, GK Panigrahi - Molecular Biotechnology, 2024 - Springer
Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved surveillance
mechanism in eukaryotes primarily deployed to ensure RNA quality control by eliminating …
mechanism in eukaryotes primarily deployed to ensure RNA quality control by eliminating …
In Vitro Cross-Linking MS Reveals SMG1–UPF2–SMG7 Assembly as Molecular Partners within the NMD Surveillance
M Padariya, B Vojtesek, T Hupp… - International Journal of …, 2024 - mdpi.com
mRNAs containing premature stop codons are responsible for various genetic diseases as
well as cancers. The truncated proteins synthesized from these aberrant mRNAs are seldom …
well as cancers. The truncated proteins synthesized from these aberrant mRNAs are seldom …
Keap1-resistant ΔN-Nrf2 isoform does not translocate to the nucleus upon electrophilic stress
S Mikac, A Dziadosz, M Padariya, U Kalathiya… - bioRxiv, 2022 - biorxiv.org
The Nrf2 pathway is an essential defense pathway in a cell. It responds to oxidative and
electrophilic stress via derepression of Nrf2 from Keap1-Cul3-mediated degradation …
electrophilic stress via derepression of Nrf2 from Keap1-Cul3-mediated degradation …
The Binding Specificity of PAB1 with Poly (A) mRNA, Regulated by Its Structural Folding
M Padariya, U Kalathiya - Biomedicines, 2022 - mdpi.com
The poly (A)-binding protein cytoplasmic 1 (PAB1 or PABPC1) protein is associated with the
long poly (A) mRNA tails, inducing stability. Herein, we investigated the dynamics of the …
long poly (A) mRNA tails, inducing stability. Herein, we investigated the dynamics of the …
[PDF][PDF] Identification of a novel, transcription-independent role of Nrf2 in lung cells
S Mikac - 2022 - bip.ug.edu.pl
The transcription factor Nrf2 is recognized for its pro-survival and cell-protective role upon
exposure to different types of extrinsic and intrinsic insults. It controls a number of cellular …
exposure to different types of extrinsic and intrinsic insults. It controls a number of cellular …
[PDF][PDF] The Binding Specificity of PAB1 with Poly (A) mRNA, Regulated by Its Structural Folding. Biomedicines 2022, 10, 2981
M Padariya, U Kalathiya - 2022 - repozytorium.bg.ug.edu.pl
The poly (A)-binding protein cytoplasmic 1 (PAB1 or PABPC1) protein is associated with the
long poly (A) mRNA tails, inducing stability. Herein, we investigated the dynamics of the …
long poly (A) mRNA tails, inducing stability. Herein, we investigated the dynamics of the …