Biotechnological and pharmacological applications of biotoxins and other bioactive molecules from dinoflagellates

J Assunção, AC Guedes, FX Malcata - Marine Drugs, 2017 - mdpi.com
The long-lasting interest in bioactive molecules (namely toxins) produced by (microalga)
dinoflagellates has risen in recent years. Exhibiting wide diversity and complexity, said …

Environmental Factors Modulate Saxitoxins (STXs) Production in Toxic Dinoflagellate Alexandrium: An Updated Review of STXs and Synthesis Gene Aspects

QTN Bui, B Pradhan, HS Kim, JS Ki - Toxins, 2024 - mdpi.com
The marine dinoflagellate Alexandrium is known to form harmful algal blooms (HABs) and
produces saxitoxin (STX) and its derivatives (STXs) that cause paralytic shellfish poisoning …

Toxin production of dinoflagellate Gymnodinium catenatum isolated from the East China Sea

ZR Lin, HX Geng, QC Zhang, ZF Chen, L Dai, RC Yu - Harmful Algae, 2022 - Elsevier
Dinoflagellate Gymnodinium catenatum is an important producer of paralytic shellfish toxins
(PSTs), including a novel group of hydroxybenzoate derivatives named GC toxins. In the …

Electrochemical immunosensor functionalized with nanobodies for the detection of the toxic microalgae Alexandrium minutum using glassy carbon electrode modified …

S Oloketuyi, E Mazzega, J Zavašnik… - Biosensors and …, 2020 - Elsevier
In this work an electrochemical immunosensor for the toxic microalgae Alexandrium
minutum (A. minutum AL9T) detection is described. A glassy carbon electrode (GCE) was …

Temperature influences the content and biosynthesis gene expression of saxitoxins (STXs) in the toxigenic dinoflagellate Alexandrium pacificum

H Wang, H Kim, H Park, JS Ki - Science of The Total Environment, 2022 - Elsevier
Temperature may affect the production of saxitoxin (STX) and its derivatives (STXs);
however, this is still controversial. Further, STX-biosynthesis gene regulation and the …

Effects of nitrate on the saxitoxins biosynthesis revealed by sxt genes in the toxic dinoflagellate Alexandrium pacificum (group IV)

S Abassi, HS Kim, QTN Bui, JS Ki - Harmful Algae, 2023 - Elsevier
The dinoflagellate Alexandrium pacificum (group IV) is of particular interest because of its
involvement in harmful algal blooms and production of saxitoxin (STX), which causes …

Low temperature and cold stress significantly increase saxitoxins (STXs) and expression of STX biosynthesis genes sxtA4 and sxtG in the dinoflagellate Alexandrium …

H Kim, H Park, H Wang, HY Yoo, J Park, JS Ki - Marine Drugs, 2021 - mdpi.com
Toxic dinoflagellate Alexandrium spp. produce saxitoxins (STXs), whose biosynthesis
pathway is affected by temperature. However, the link between the regulation of the relevant …

Toxicity and Growth Assessments of Three Thermophilic Benthic Dinoflagellates (Ostreopsis cf. ovata, Prorocentrum lima and Coolia monotis) Developing in the …

H Ben-Gharbia, OKD Yahia, Z Amzil, N Chomérat… - Toxins, 2016 - mdpi.com
Harmful benthic dinoflagellates, usually developing in tropical areas, are expanding to
temperate ecosystems facing water warming. Reports on harmful benthic species are …

Saxitoxins-producing potential of the marine dinoflagellate Alexandrium affine and its environmental implications revealed by toxins and transcriptome profiling

HS Kim, H Park, H Wang, T Kim, JS Ki - Marine Environmental Research, 2023 - Elsevier
The marine dinoflagellate Alexandrium occurs widely in coastal waters, and some of them
can produce saxitoxins (STXs) that cause paralytic shellfish poisoning (PSP). Alexandrium …

[HTML][HTML] Apparent biogeographical trends in Alexandrium blooms for northern Europe: identifying links to climate change and effective adaptive actions

K Klemm, A Cembella, D Clarke, C Cusack, L Arneborg… - Harmful Algae, 2022 - Elsevier
Abstract The marine dinoflagellate Alexandrium Halim represents perhaps the most
significant and intensively studied genus with respect to species diversity, life history …