GBM is the most common, aggressive, and intracranial primary brain tumor; it originates from
the glial progenitor cells, has poor overall survival (OS), and has limited treatment options. In …

Glioblastoma is the most common primary malignant brain tumor in adults and outcomes
remain poor despite the current standard of care multimodal therapy. Oncolytic virotherapy …

Glioblastoma is the most common malignant primary brain tumor in adults. Despite treatment
consisting of surgical resection followed by radiotherapy and adjuvant chemotherapy …

Oncolytic virotherapy is a promising therapeutic approach for glioblastoma (GBM) treatment,
although the outcomes are partially satisfactory. Hence, more effective strategies are …

Glioblastoma multiforme (GBM), as one of the most common malignant brain tumors, was
limited in its treatment effectiveness with current options. Its invasive and infiltrative features …

Primary, glioblastoma, and secondary brain tumors, from metastases outside the brain, are
among the most aggressive and therapeutically resistant cancers. A physiological barrier …

Background Diffuse gliomas are the most common primary central nervous system tumor in
adults and can be classified by histology and molecular alternations into grade 2 to 4 …

Simple Summary Glioma is a life-threatening malignancy where conventional therapies are
ineffective, and microorganisms are a promising weapon that can be used in cancer …

Human artificial chromosomes (HACs) are gene delivery vectors that have been used for
decades for gene functional studies. HACs have several advantages over viral‐based gene …

Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset
site, combined with the infiltrative properties of this tumor, require novel targeted therapies …