Skeletal muscle is the largest organ of human body with several important roles in everyday
movement and metabolic homeostasis. The limited ability of small animal models of muscle …

Introduction: The need to improve drug research and development productivity continues to
drive innovation in pharmacological assays. Technologies that can leverage the advantages …

This study demonstrates the growth and differentiation of C2C12 myoblasts into functional
myotubes on three-dimensional graphene foam bioscaffolds. Specifically, we establish both …

While several functional platforms for cell culturing have been proposed for cell sheet
engineering, a soft integrated system enabling in vitro physiological monitoring of aligned …

The accurate measurement of the morphological characteristics of cells with nonuniform
conformations presents difficulties. We report here a straightforward method using …

Objective We have recently reported on the pathology of the neuromuscular junction (NMJ)
in Pompe disease, reflecting disruption of neuronal and muscle homeostasis as a result of …

Background Electrical impedance myography and quantitative ultrasound are two
noninvasive, painless, and effort-independent approaches for assessing neuromuscular …

The high regenerative capacity of adult skeletal muscle relies on a self-renewing depot of
adult stem cells, termed muscle satellite cells (MSCs). Androgens, known mediators of …

Electrical impedance measurements of skeletal muscle may be sensitive to age-associated
declines in muscle health. In an effort to evaluate this concept further, we performed …

In this study, we present a first-of-a-kind biological-hardware-software tool to evaluate the
physiological condition of in vitro myotubes in response to electrical stimulation. We …