[HTML][HTML] Advancements in nano drug delivery system for liver cancer therapy based on mitochondria-targeting

L Chen, Y He, J Lan, Z Li, D Gu, W Nie, T Zhang… - Biomedicine & …, 2024 - Elsevier
Based on poor efficacy and non-specific toxic side effects of conventional drug therapy for
liver cancer, nano-based drug delivery system (NDDS) offers the advantage of drug …

Novel sulfonamides unveiled as potent anti-lung cancer agents via tumor pyruvate kinase M2 activation

R Das, DR Chatterjee, S Kapoor, H Vyas… - RSC Medicinal …, 2024 - pubs.rsc.org
This rational pursuit led to the identification of a novel sulfonamide derivative as a potent anti-
lung cancer (LC) compound. Considering these results, we synthesized 38 novel …

Synthesis and characterization of phenoxy-bridged copper (II) complexes: Structural features, magnetic, thermal and redox properties, and theoretical studies

M Choudhary - Inorganica Chimica Acta, 2023 - Elsevier
Three phenoxy-bridged Cu (II) complexes, a trinuclear partial cubane type Cu (II) complex
[Cu 3 (L 1) 3 (µ 3-OH)](ClO 4) 2 (1)(where L 1 H=(E)-2-(((2-aminoethyl) imino) methyl)-5 …

Cocrystallization of 5-FU and novel sulfathiazole Schiff bases: Synthesis, theoretical and experimental anticancer evaluation against MCF-7 and SW-480 cancer cell …

A Aslam, A Parveen, N Bano, I Jabeen… - Journal of Molecular …, 2025 - Elsevier
The pharmaceutical industry is advancing toward the precise engineering of customized
dosage forms through the manipulation of solid-state properties. This study reports drug …

Novel metal (II) complexes with 2, 2'-bithiophene ligands as promising antibacterial agents: Spectral investigation, electrochemical behavior, DFT studies, in vitro and …

KS Larbi, A Bouchoucha, MA Bourouai… - Journal of Molecular …, 2023 - Elsevier
The present study reports the synthesis, characterization, electrochemical behavior, and
antimicrobial potential of novel bithiophene derivatives and their nickel (II) and copper (II) …

New sulfa drug derivatives and their zinc (II) complexes: synthesis, spectroscopic properties and in vitro cytotoxic activities

H Şahal, S Öz, T Keskin, S Tekin… - Journal of …, 2024 - Taylor & Francis
Synthesis of four sulfa drug derivatives (L1–L4) and Zn (II) complexes derived from
sulfonamide group antibiotic substances was carried out using the hydrothermal technique …

Stearyl palmitate a multi-target inhibitor against breast cancer: in-silico, in-vitro & in-vivo approach

L Ravi, A Kumar K, S Kumari GR… - Journal of …, 2024 - Taylor & Francis
Multi-target inhibitors are currently trending in the pharmaceutical research, as they possess
increased efficacy and reduced toxicity. In this study multi-target inhibitors for breast cancer …

[PDF][PDF] Synthesis, crystal structure and in-silico evaluation of arylsulfonamide Schiff bases for potential activity against colon cancer

SO Kolade, OS Aina, AT Gordon… - … Section C: Structural …, 2024 - journals.iucr.org
This report presents a comprehensive investigation into the synthesis and characterization
of Schiff base compounds derived from benzenesulfonamide. The synthesis process …

Transition Metal Complexes of 2-Aminopyridine Derivatives as Cyclooxygenase Inhibitors: Stability, Spectral, and Thermal Characterization, Electrochemical Behavior …

K Beddar, A Bouchoucha, MA Bourouai… - Russian Journal of …, 2023 - Springer
A series of Mn (II), Fe (III), and Co (II), complexes with two ligands derived from 2-
aminopyridine, 4-hydroxy-2-methyl-N-(2-pyridyl)-2 H-1, 2-benzothiazine-3-carboxamide 1, 1 …

Fluorene-based Schiff bases with potent absorption and emissive characteristics

A Sreekumar, A Manoj, KK Priyanka, S Priyanka… - Materials Today …, 2024 - Elsevier
Since its discovery by Marcellin Berthelot in 1867, there have been humongous studies
based on the synthesis and application of fluorene and its descendent compounds. The …