Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic
option for many disorders. However, poor bioavailability and selectivity might limit their …

Kaempferol and its derivatives are naturally occurring phytochemicals with promising
bioactivities. This flavonol can reduce the lipid oxidation in the human body, prevent the …

Although active constituents extracted from plants show robust in vitro pharmacological
effects, low in vivo absorption greatly limits the widespread application of these compounds …

Skin being the outermost layer of the body is most prone to the damages caused by direct
exposure of the UV radiation emitted in the atmosphere. Sunscreens are developed to …

COVID‐19 has infected 272 million patients and caused 5.33 million deaths around the
world, and it remains the main global threat. Previous studies revealed that Chinese …

The current study was aimed to develop an amphiphilic drug-lipid nano-complex of rutin:
egg phosphatidylcholine (EPC) to enhance its poor absorption and bioavailability, and …

In this study, self-assembled phytosomal soft nanoparticles encapsulated with phospholipid
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …

The formation of cocrystals is closely related to the weak interaction between the participant
molecules. Among the factors that influence the interaction between molecules in a …

Atorvastatin (ATV), a lipid-lowering agent, has low oral bioavailability due to its poor water
solubility, permeability, and low dissolution rate. Therefore, pentaerythritol-EudragitRS100 …

Abstract Genistein (GEN), an isoflavonoid, offers multifunctional biological activities.
However, its poor oral bioavailability, aqueous solubility, extensive metabolism, and short …