The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review

T Fiolet, Y Kherabi, CJ MacDonald, J Ghosn… - Clinical Microbiology …, 2022 - Elsevier
Background Vaccines are critical cost-effective tools to control the coronavirus disease 2019
(COVID-19) pandemic. However, the emergence of variants of the severe acute respiratory …

Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

A Pegu, SE O'Connell, SD Schmidt, S O'Dell… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish
vaccine-induced protective immune responses, particularly as antibody titers wane over …

The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines

G McLean, J Kamil, B Lee, P Moore, TF Schulz, A Muik… - MBio, 2022 - Am Soc Microbiol
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …

Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD

NA Kennedy, S Lin, JR Goodhand, N Chanchlani… - Gut, 2021 - gut.bmj.com
Objective Delayed second dose SARS-CoV-2 vaccination trades maximal effectiveness for a
lower level of immunity across more of the population. We investigated whether patients with …

[PDF][PDF] Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant

KE Lyke, RL Atmar, CD Islas, CM Posavad… - Cell Reports …, 2022 - cell.com
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
exhibits reduced susceptibility to vaccine-induced neutralizing antibodies, requiring a boost …

SARS-CoV-2 mRNA vaccines induce broad CD4+ T cell responses that recognize SARS-CoV-2 variants and HCoV-NL63

BA Woldemeskel, CC Garliss… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Recent studies have shown T cell cross-recognition of SARS-CoV-2 and common cold
coronavirus spike proteins. However, the effect of SARS-CoV-2 vaccines on T cell …

[HTML][HTML] Laboratory-confirmed COVID-19 among adults hospitalized with COVID-19–like illness with infection-induced or mRNA vaccine-induced SARS-CoV-2 …

CH Bozio - MMWR. Morbidity and Mortality Weekly Report, 2021 - cdc.gov
Among COVID-19–like illness hospitalizations among adults aged≥ 18 years whose
previous infection or vaccination occurred 90–179 days earlier, the adjusted odds of …

Differential antibody response to mRNA COVID-19 vaccines in healthy subjects

SE Wheeler, GV Shurin, M Yost, A Anderson… - Microbiology …, 2021 - Am Soc Microbiol
Knowledge about development and duration of virus-specific antibodies after COVID-19
vaccination is important for understanding how to limit the pandemic via vaccination in …