Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Regulation of the tumor suppressor PTEN in triple-negative breast cancer

C Chai, HH Wu, Y Abuetabh, C Sergi, R Leng - Cancer letters, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer (BCa) in which estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

Comparison of PIK3CA Mutation Prevalence in Breast Cancer Across Predicted Ancestry Populations

JW Chen, K Murugesan, JY Newberg… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Understanding the differences in biomarker prevalence that may exist among
diverse populations is invaluable to accurately forecast biomarker-driven clinical trial …

Cryoablation of primary breast cancer tumors induces a systemic abscopal effect altering TIME (Tumor Immune Microenvironment) in distant tumors

F Sardela de Miranda, D Martinez-Marin… - Frontiers in …, 2024 - frontiersin.org
Introduction Despite recent advances, triple-negative breast cancer (TNBC) patients remain
at high risk for recurrence and metastasis, which creates the need for innovative therapeutic …

The association of PTEN gene mutations with the breast cancer risk: A systematic review and meta-analysis

K Yari, A Hakimi, M Mohammadi… - Biochemical …, 2024 - Springer
Breast cancer (BC) is the most common malignancy in women in western countries. A
significant part of malignant cases is caused by genetic mutation. Mutations in the gene …

Characteristics of recurrence, predictors for relapse and prognosis of rapid relapse triple-negative breast cancer

SL Cai, JJ Liu, YX Liu, SH Yu, X Liu, XQ Lin… - Frontiers in …, 2023 - frontiersin.org
Background Triple-negative breast cancer (TNBC) patients who recur at different times are
associated with distinct biological characteristics and prognoses. Research on rapid-relapse …

Epithelioid and spindle rhabdomyosarcoma with TFCP2 rearrangement in abdominal wall: a distinctive entity with poor prognosis

Y Li, D Li, J Wang, J Tang - Diagnostic Pathology, 2023 - Springer
Background Epithelioid and spindle rhabdomyosarcoma (ES-RMS) with TFCP2
rearrangement is a recently discovered rare variant of rhabdomyosarcoma composed of …

Significance of Multi-Cancer Genome Profiling Testing for Breast Cancer: A Retrospective Analysis of 3326 Cases from Japan's National Database

K Kawabata, H Nishikubo, S Kanei, R Aoyama… - Genes, 2024 - mdpi.com
Background: Breast cancer (BC) has the highest morbidity rate and the second-highest
mortality rate of all cancers among women. Recently, multi-cancer genome profiling (multi …

TGF-β1 and FOXM1 siRNA co-loaded nanoparticles by disulfide crosslinked PEG-PDMAEMA for the treatment of triple-negative breast cancer and its bone …

X Wang, H Huang, W Xu, Y Gong, S Shi… - Drug Development …, 2024 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) is characterized by higher malignancy
and mortality and is prone to distant metastasis, among which bone is the most common site …

[HTML][HTML] The pathological and clinical landscape of refractory metastatic triple negative breast cancer: a narrative review

MP Jiang, X Huang, YM Yin, JH Tang - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Methods Recent domestic and foreign guidelines, as well as clinical studies related to
refractory mTNBC on PubMed and the China National Knowledge Infrastructure (CNKI) …