Publisher Summary Carcinoma, cancer of epithelial cells, is a major cause of morbidity and
mortality. Clonal fixation and propagation of oncogenic genetic changes, sporadically …

This book on the World Health Organization (WHO) classification of tumours of the nervous
system reflects the view of a working group that convened for an editorial and consensus …

Overexpression of epidermal growth factor receptor (EGFR, ErbB1) correlates with
enhanced malignant potential of many human tumor types including glioblastoma …

The HLA-G and HLA-E molecules, Ki67, progesterone (PR), estrogen (ER) and androgen
receptors (AR), p53, COX-2, and HER2 were studied to assess whether the biological …

Introduction Epidermal growth factor receptors EGFR and ErbB2 are overexpressed in
schwannomas and meningiomas. Preclinical and clinical data indicate that lapatinib, an …

C-erb B2/HER2 serves as an important prognostic and predictive biomarker in various
human tumors, especially in breast cancer, whereas its role in human intracranial tumors is …

Although tumour recurrence is an important and not infrequent event in meningiomas,
predictive immunohistochemical markers have not been identified yet. The aim of this study …

The aggressiveness of meningiomas is unpredictable. HER2 represents a well-known
prognostic factor in various tumors such as breast carcinomas. This work was designed to …

Meningiomas are common types of adult nerve system tumors. Although most cases are
considered benign, due to its high rate of recurrence and easy malignant progression to …

Abstract The 2007 World Health Organization histologic grading of meningiomas is
associated with recurrence and clinical outcome. However, distinction of grade I from grade …