Recent progress in the nitration of arenes and alkenes

YE Qian, L Zheng, HY Xiang, H Yang - Organic & Biomolecular …, 2021 - pubs.rsc.org
Nitro compounds are a predominant class of synthetic intermediates and building blocks for
the preparation of a wide range of nitrogen-containing compounds in the chemical industry …

Organic nitrating reagents

S Patra, I Mosiagin, R Giri, D Katayev - Synthesis, 2022 - thieme-connect.com
Nitro compounds are vital raw chemicals that are widely used in academic laboratories and
industries for the preparation of various drugs, agrochemicals, and materials. Thus, nitrating …

Theoretical insight into electronic and molecular properties of halogenated (F, Cl, Br) and hetero-atom (N, O, S) doped cyclooctane

JA Agwupuye, H Louis, OC Enudi, TO Unimuke… - Materials Chemistry and …, 2022 - Elsevier
Undoubtedly, cyclooctane has been investigated theoretically and experimentally, however,
considering the vast application of cycloalkanes and limited research for the higher …

Copper catalyzed late-stage C(sp3)-H functionalization of nitrogen heterocycles

Z Chang, J Huang, S Wang, G Chen, H Zhao… - Nature …, 2021 - nature.com
Nitrogen heterocycle represents a ubiquitous skeleton in natural products and drugs. Late-
stage C (sp3)-H bond functionalization of N-heterocycles with broad substrate scope …

Metal-free enaminone C–N bond cyanation for the stereoselective synthesis of (E)-and (Z)-β-cyano enones

T Liu, JP Wan, Y Liu - Chemical Communications, 2021 - pubs.rsc.org
A highly practical method for C–CN bond formation by C–N bond cleavage on enaminones
leading to the efficient synthesis of β-cyano enones is developed. The reactions take place …

Hypervalent iodine (iii)-mediated oxidative dearomatization of 2 H-indazoles towards indazolyl indazolones

S Bhattacharjee, S Laru, A Hajra - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
A new iodine (III)-mediated oxidative dearomatization of 2H-indazoles has been developed
to afford N-1 indazolyl indazolones. In this methodology, PIFA plays a dual role: as an …

Phenyliodine bis (trifluoroacetate) as a sustainable reagent: exploring its significance in organic synthesis

S Kumar, A Arora, SK Singh, R Kumar… - Organic & …, 2024 - pubs.rsc.org
Iodine-containing molecules have garnered substantial attention in the realm of organic
synthesis during recent decades. Higher oxidation state iodine compounds, often denoted …

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

M Dichiara, FA Ambrosio, SM Lee… - Journal of Medicinal …, 2023 - ACS Publications
The design and synthesis of a series of 2, 7-diazaspiro [4.4] nonane derivatives as potent
sigma receptor (SR) ligands, associated with analgesic activity, are the focus of this work. In …

Flavin nitroalkane oxidase mimics compatibility with NOx/TEMPO catalysis: aerobic oxidization of alcohols, diols, and ethers

P Thapa, S Hazoor, B Chouhan, TT Vuong… - The Journal of …, 2020 - ACS Publications
Biomimetic flavin organocatalysts oxidize nitromethane to formaldehyde and NO x—
providing a relatively nontoxic, noncaustic, and inexpensive source for catalytic NO2 for …

Regioselective α-cyanation of unprotected alicyclic amines

F Yu, DA Valles, W Chen, SD Daniel, I Ghiviriga… - Organic …, 2022 - ACS Publications
Secondary alicyclic amines are converted to α-aminonitriles via addition of TMSCN to their
corresponding imines, intermediates that are produced in situ via the oxidation of amine …