Structural aspects of solid solutions of enantiomers

C Brandel, S Petit, Y Cartigny… - Current Pharmaceutical …, 2016 - ingentaconnect.com
A mixture of two enantiomers can crystallize according to three types of heterogeneous
equilibria: a racemic compound (a 1: 1 stoichiometric compound), a conglomerate (a …

Relevance of the second harmonic generation to characterize crystalline samples

F Simon, S Clevers, V Dupray… - Chemical Engineering & …, 2015 - Wiley Online Library
The application of powder second harmonic generation (P‐SHG), temperature‐resolved
SHG (TR‐SHG), and SHG microscopy (SHGM) in the characterization of bulk crystalline …

The persistence and crystallization behavior of atorvastatin calcium amorphous dispersions in polyvinylpyrrolidone

C Tizaoui, H Galai, S Clevers, N Couvrat… - Journal of Drug Delivery …, 2022 - Elsevier
The persistence of amorphous atorvastatin calcium has been studied as a function of the
amorphization method, polymer content, and relative humidity during storage. For …

Monotropic Transition Mechanism of m-Hydroxybenzoic Acid Investigated by Temperature-Resolved Second Harmonic Generation

S Clevers, F Simon, M Sanselme, V Dupray… - Crystal growth & …, 2013 - ACS Publications
Temperature-resolved second harmonic generation (TR-SHG) and SHG microscopy were
used to study under normal pressure the solid–solid transition mechanism occurring …

Crystallization of chiral molecules

C Viedma, G Coquerel, P Cintas - Handbook of Crystal Growth, 2015 - Elsevier
Chirality plays a pivotal role in contemporary science as it represents a distinctive feature
found in molecules and crystals. This chapter constitutes an excursion into solid-state …

Powders analysis by second harmonic generation microscopy

AU Chowdhury, S Zhang, GJ Simpson - Analytical chemistry, 2016 - ACS Publications
A microscopy approach is developed for quantifying second harmonic generation (SHG)
activity of powders that largely decouples linear and nonlinear optical interactions …

New intermediate polymorph of 1-Fluoro-adamantane and its second-order-like transition toward the low temperature phase

L Yuan, S Clevers, A Burel, P Negrier… - Crystal Growth & …, 2017 - ACS Publications
Phase transitions of 1-fluoro-adamantane have been thoroughly investigated by
temperature-resolved second harmonic generation (TR-SHG) and X-ray powder diffraction …

A Racemic and Enantiopure Unsymmetric Diiron(III) Complex with a Chiral o‐Carborane‐Based Pyridylalcohol Ligand: Combined Chiroptical, Magnetic, and …

F Di Salvo, MY Tsang, F Teixidor… - … A European Journal, 2014 - Wiley Online Library
The design of molecule‐based systems combining magnetic, chiroptical and second‐order
optical nonlinear properties is still very rare. We report an unusually unsymmetric diiron (III) …

Ab initio prediction of the diversity of second harmonic generation from pharmaceutically relevant materials

SJ Toth, PD Schmitt, GR Snyder, NS Trasi… - Crystal Growth & …, 2015 - ACS Publications
A model for predicting the anticipated second harmonic generation (SHG) activity of
crystalline active pharmaceutical ingredients (APIs) was developed based on combining …

Enhanced second harmonic generation from an organic self-assembled eutectic binary mixture: a case study with 3-nitrobenzoic and 3, 5-dinitrobenzoic acids

F Simon, S Clevers, G Gbabode, N Couvrat… - Crystal Growth & …, 2015 - ACS Publications
This work illustrates the use of powder second harmonic generation (powder SHG),
temperature-resolved second harmonic generation (TR-SHG), and second harmonic …