Evaluating the effect of setup uncertainty reduction and adaptation to geometric changes on normal tissue complication probability using online adaptive head and …

A Lalonde, M Bobić, GC Sharp… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. To evaluate the impact of setup uncertainty reduction (SUR) and adaptation to
geometrical changes (AGC) on normal tissue complication probability (NTCP) when using …

[HTML][HTML] Does adaptive radiotherapy for head and neck cancer favorably impact dosimetric, clinical, and toxicity outcomes?: A review

F Simopoulou, G Kyrgias, I Georgakopoulos… - Medicine, 2024 - journals.lww.com
Purpose: The current review aims to summarize the international experience of the impact of
adaptive radiotherapy on dosimetry and clinical and toxicity outcomes. Additionally, it might …

Optically stimulated luminescence dosimeters for simultaneous measurement of point dose and dose-weighted LET in an adaptive proton therapy workflow

M Bobić, JB Christensen, H Lee, E Choulilitsa… - Frontiers in …, 2024 - frontiersin.org
Purpose To demonstrate the suitability of optically stimulated luminescence detectors
(OSLDs) for accurate simultaneous measurement of the absolute point dose and dose …

A fast and robust constraint-based online re-optimization approach for automated online adaptive intensity modulated proton therapy in head and neck cancer

M Oud, S Breedveld, J Rojo-Santiago… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. In head-and-neck cancer intensity modulated proton therapy, adaptive
radiotherapy is currently restricted to offline re-planning, mitigating the effect of slow …

A retrospective study on the investigation of potential dosimetric benefits of online adaptive proton therapy for head and neck cancer

CW Chang, D Bohannon, Z Tian… - Journal of Applied …, 2024 - Wiley Online Library
Purpose Proton therapy is sensitive to anatomical changes, often occurring in head‐and‐
neck (HN) cancer patients. Although multiple studies have proposed online adaptive proton …

Surveying the clinical practice of treatment adaptation and motion management in particle therapy

B Knäusl, VT Taasti, P Poulsen… - Physics and Imaging in …, 2023 - phiro.science
Due to the limited number of particle therapy centres worldwide, the outcome of these two
surveys is very powerful and proved a broad overview of actual clinical practice. Assessing …

Multi-institutional experimental validation of online adaptive proton therapy workflows

M Bobić, E Choulilitsa, H Lee, K Czerska… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. To experimentally validate two online adaptive proton therapy (APT) workflows
using Gafchromic EBT3 films and optically stimulated luminescent dosimeters (OSLDs) in an …

An operator-independent quality assurance system for automatically generated structure sets

A Bookbinder, M Bobić, GC Sharp… - Physics in Medicine & …, 2024 - iopscience.iop.org
Objective. This study describes geometry-based and intensity-based tools for quality
assurance (QA) of automatically generated structures for online adaptive radiotherapy, and …

[HTML][HTML] Proton Therapy Adaptation of Perisinusoidal and Brain Areas in the Cyclotron Centre Bronowice in Krakow: A Dosimetric Analysis

M Rydygier, T Skóra, K Kisielewicz, A Spaleniak… - Cancers, 2024 - mdpi.com
Simple Summary Adaptive proton therapy (APT) is an evolving approach to proton beam
scanning treatment planning. We performed dosimetric study on two groups of head and …

The partial adaptation strategy for online‐adaptive proton therapy: A proof of concept study in head and neck cancer patients

V Gambetta, A Fredriksson, S Menkel… - Medical …, 2024 - Wiley Online Library
Background The accuracy of intensity‐modulated proton therapy (IMPT) is greatly affected
by anatomy variations that might occur during the treatment course. Online plan adaptations …