特发性肺纤维化是一种慢性的进行性肺部疾病, 它也是特发性间质性肺炎最常见的形式之一,
具有很高死亡率, 自诊断之日起中位生存期仅为2~ 3 年. 尽管其发病机制尚不明确 …

Ligamentum flavum (LF) hypertrophy is a major cause of lumbar spinal canal stenosis.
Although mechanical stress is thought to be a major factor involved in LF hypertrophy, the …

Mechanical stress promotes human ligamentum flavum cells (LFCs) to synthesize multitype
collagens, leading to ligamentum flavum hypertrophy (LFH). However, the mechanism of …

The study investigates molecular changes in the lumbosacral (L/S) spine's yellow
ligamentum flavum during degenerative stenosis, focusing on the role of transforming …

Purpose To analyze the differential transcriptome expression in hypertrophic ligaments
flavum (HLF) compared to normal ligaments. Methods A case–control study was conducted …

Cell shape determines cell activities and behavior. Quantitative analysis of cell shape can
be performed by computational image-based analysis. Therefore, the aim of this study was …

Bisphosphonate (BP) and geranylgeraniol (GGOH) are known drug/reagent affecting
osteoblast shape and dimensions. Digital image analysis such as ImageJ can detect …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease. It is one of the most
common forms of idiopathic interstitial pneumonia with high mortality rate. The median …