Lycopene as a natural antioxidant used to prevent human health disorders

M Imran, F Ghorat, I Ul-Haq, H Ur-Rehman, F Aslam… - Antioxidants, 2020 - mdpi.com
Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in
tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant …

Role of natural phenolics in hepatoprotection: a mechanistic review and analysis of regulatory network of associated genes

P Saha, AD Talukdar, R Nath, SD Sarker… - Frontiers in …, 2019 - frontiersin.org
The liver is not only involved in metabolism and detoxification, but also participate in innate
immune function and thus exposed to frequent target Thus, they are the frequent target of …

Synergistic protective effects of lycopene and N-acetylcysteine against cisplatin-induced hepatorenal toxicity in rats

A Elsayed, A Elkomy, R Elkammar, G Youssef… - Scientific Reports, 2021 - nature.com
Cisplatin (CP) is one of the most frequently used chemotherapy agents. The objective of this
design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine …

Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR–Nrf2 pathway

Y Zhao, RK Bao, SY Zhu, M Talukder, JG Cui… - Environmental …, 2021 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a widespread plasticizer that persists in the
environment and can significantly contribute to serious health hazards of liver especially …

[HTML][HTML] Protective effects of lycopene on mitochondrial oxidative injury and dysfunction in the liver of aflatoxin B1-exposed broilers

XL Wan, N Li, YJ Chen, XS Chen, Z Yang, L Xu… - Poultry Science, 2021 - Elsevier
This study was conducted to investigate the effects of lycopene (LYC) on mitochondrial
oxidative injury and dysfunction in the liver of aflatoxin B 1 (AFB 1)-exposed broilers. A total …

Promising hepatoprotective effects of lycopene in different liver diseases

IM Ibrahim, HS Althagafy, EK Abd-Alhameed… - Life Sciences, 2022 - Elsevier
The incidence of liver diseases such as hepatitis, fibrosis, cirrhosis, and liver cancer is one
of the world's most significant health challenges. Liver diseases can be caused by a variety …

Exopolysaccharides from Lactobacillus buchneri TCP016 Attenuate LPS- and d-GalN-Induced Liver Injury by Modulating the Gut Microbiota

R Xu, Aruhan, L Xiu, S Sheng, Y Liang… - Journal of agricultural …, 2019 - ACS Publications
Liver diseases alter the gut microbiota, but several lactic acid bacteria can reduce the
degree of liver damage. The present study investigated whether Lactobacillus buchneri …

Antioxidant Properties of Salvia officinalis Decoction Extract and Mechanism of Its Protective Effects on Ethanol-Induced Liver and Kidney Injuries

S Jedidi, F Aloui, S Selmi, H Selmi… - Journal of Medicinal …, 2022 - liebertpub.com
This study assessed the hepato-and nephroprotective effects of Salvia officinalis flowers
decoction extract (SODE) against ethanol (EtOH)-induced oxidative stress in rats as well as …

[HTML][HTML] Anti‑apoptotic effects of human placental hydrolysate against hepatocyte toxicity in vivo and in vitro

DH Bak, J Na, MJ Choi, BC Lee… - International …, 2018 - spandidos-publications.com
Apoptosis and oxidative stress are essential for the pathogenesis of acute liver failure and
fulminant hepatic failure. Human placental hydrolysate (hPH) has been reported to possess …

Therapeutic effect of lycopene in lipopolysaccharide nephrotoxicity through alleviation of mitochondrial dysfunction, inflammation, and oxidative stress

S Salari, A Ghorbanpour, N Marefati… - Molecular Biology …, 2022 - Springer
Background Sepsis-associated acute kidney injury (AKI) accompanies a higher mortality in
intensive care patients. High-dose lipopolysaccharides (LPS) as an endotoxin is usually …