Characterizing extracellular vesicles and their diverse RNA contents

EM Veziroglu, GI Mias - Frontiers in Genetics, 2020 - frontiersin.org
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …

[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

Human aquaporin-5 facilitates hydrogen peroxide permeation affecting adaption to oxidative stress and cancer cell migration

C Rodrigues, C Pimpão, AF Mósca, AS Coxixo… - Cancers, 2019 - mdpi.com
Reactive oxygen species (ROS), including H2O2, contribute to oxidative stress and may
cause cancer initiation and progression. However, at low concentrations, H2O2 can regulate …

Involvement of aquaporin 5 in Sjögren's syndrome

C Chivasso, C D'Agostino, D Parisis, MS Soyfoo… - Autoimmunity …, 2023 - Elsevier
Sjögren's syndrome (SS) is a chronic autoimmune disease with the pathological hallmark of
lymphoplasmacytic infiltration of exocrine glands-more specifically salivary and lacrimal …

Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Insight into salivary gland aquaporins

C D'Agostino, OA Elkashty, C Chivasso, J Perret… - Cells, 2020 - mdpi.com
The main role of salivary glands (SG) is the production and secretion of saliva, in which
aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane …

Phosphorylation-dependent regulation of mammalian aquaporins

V Nesverova, S Törnroth-Horsefield - Cells, 2019 - mdpi.com
Water homeostasis is fundamental for cell survival. Transport of water across cellular
membranes is governed by aquaporins—tetrameric integral membrane channels that are …

Aquaporin protein-protein interactions

JV Roche, S Törnroth-Horsefield - International journal of molecular …, 2017 - mdpi.com
Aquaporins are tetrameric membrane-bound channels that facilitate transport of water and
other small solutes across cell membranes. In eukaryotes, they are frequently regulated by …

Aquaporin-5: from structure to function and dysfunction in cancer

I Direito, A Madeira, MA Brito, G Soveral - Cellular and Molecular Life …, 2016 - Springer
Aquaporins, a highly conserved group of membrane proteins, are involved in the
bidirectional transfer of water and small solutes across cell membranes taking part in many …