Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Congenital myasthenic syndromes (CMS) are a heterogeneous group of disorders
characterized by impaired neuromuscular signal transmission due to germline pathogenic …

Muscle-specific tyrosine kinase myasthenia gravis (MuSK MG) is an autoimmune disease
that causes life-threatening muscle weakness due to anti-MuSK autoantibodies that disrupt …

The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …

Myasthenia gravis (MG) is an autoimmune disorder caused by autoantibodies that target the
neuromuscular junction, leading to muscle weakness and fatigability. Currently available …

Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …

The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …

The heterotrimeric laminins are a defining component of all basement membranes and self-
assemble into a cell-associated network. The three short arms of the cross-shaped laminin …

Cholesterol is a major constituent of the human brain, and the brain is the most cholesterol‐
rich organ. Numerous lipoprotein receptors and apolipoproteins are expressed in the brain …

The low-density lipoprotein (LDL) receptor-related protein 2 (LRP2 or megalin) is
representative of the phylogenetically conserved subfamily of giant LDL receptor-related …