Enzyme immobilization has been developing since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …

Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …

C–H deuteration has been intricately developed to satisfy the urgent need for site-selectively
deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

In industries and academic laboratories, several late transition metal-catalyzed prerequisite
reactions are widely performed during single and multistep synthesis. However, besides the …

C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …