Updates on biomaterials used in total hip arthroplasty (THA)

L Savin, T Pinteala, DN Mihai, D Mihailescu, SS Miu… - Polymers, 2023 - mdpi.com
One of the most popular and effective orthopedic surgical interventions for treating a variety
of hip diseases is total hip arthroplasty. Despite being a radical procedure that involves …

Metal-on-metal total hip arthroplasty: risk factors for pseudotumours and clinical systematic evaluation

MHL Liow, YM Kwon - International orthopaedics, 2017 - Springer
The potential advantages of contemporary MoM THA implants include less volumetric wear
with subsequent reduction of polyethylene wear-induced osteolysis and greater component …

Hyaluronic acid–British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis

CC Ude, SJ Schmidt, S Laurencin… - Proceedings of the …, 2023 - National Acad Sciences
Cobalt-containing alloys are useful for orthopedic applications due to their low volumetric
wear rates, corrosion resistance, high mechanical strength, hardness, and fatigue …

Temporal trends and survivorship of total hip arthroplasty in very young patients: a study using the National Joint Registry data set

D Metcalfe, N Peterson, JM Wilkinson… - The Bone & Joint …, 2018 - boneandjoint.org.uk
Aims The aim of this study was to describe temporal trends and survivorship of total hip
arthroplasty (THA) in very young patients, aged≤ 20 years. Patients and Methods A …

Mechanical and phase transformation behaviour of biomedical Co-Cr-Mo alloy fabricated by direct metal laser sintering

M Béreš, CC Silva, PWC Sarvezuk, L Wu… - Materials Science and …, 2018 - Elsevier
Biomedical cobalt-chromium-molybdenum (Co-Cr-Mo) alloys have been used in the cast or
wrought form as prosthetic implant materials for more than five decades. Recently, additive …

Biological effects of metal degradation in hip arthroplasties

D Granchi, LM Savarino, G Ciapetti… - Critical Reviews in …, 2018 - Taylor & Francis
Metals and metal alloys are the most used materials in orthopedic implants. The focus is on
total hip arthroplasty (THA) that, though well tolerated, may be associated with local and …

Cobalt ions induce metabolic stress in synovial fibroblasts and secretion of cytokines/chemokines that may be diagnostic markers for adverse local tissue reactions to …

F Eltit, J Noble, M Sharma, N Benam, A Haegert… - Acta Biomaterialia, 2021 - Elsevier
Adverse local tissue reactions (ALTRs) are a prominent cause of hip implant failure. ALTRs
are characterized by aseptic necrosis and leukocyte infiltration of synovial tissue. The …

Adverse reactions to metal on polyethylene implants: Highly destructive lesions related to elevated concentration of cobalt and chromium in synovial fluid

F Eltit, A Assiri, D Garbuz, C Duncan… - … Research Part A, 2017 - Wiley Online Library
Adverse local tissue reactions (ALTR) are the primary cause of failure of metal on metal
(MoM) hip implants, and fewer but not negligible number cases of nonmodular metal on …

Effect of head size and rotation on taper corrosion in a hip simulator

CM Wight, CM Whyne, ER Bogoch, R Zdero… - Bone & Joint …, 2021 - boneandjoint.org.uk
Aims This study investigates head-neck taper corrosion with varying head size in a novel hip
simulator instrumented to measure corrosion related electrical activity under torsional loads …

Gender bias in medical implant design and use: A type of moral aggregation problem?

K Hutchison - Hypatia, 2019 - cambridge.org
In this article, I describe how gender bias can affect the design, testing, clinical trials,
regulatory approval, and clinical use of implantable devices. I argue that bad outcomes …