[HTML][HTML] Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2

K Uzunova, E Filipova, V Pavlova, T Vekov - Biomedicine & …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia with an unusual
outbreak in Wuhan, China, which is caused by severe acute respiratory syndrome …

Current and future use of chloroquine and hydroxychloroquine in infectious, immune, neoplastic, and neurological diseases: a mini-review

D Plantone, T Koudriavtseva - Clinical drug investigation, 2018 - Springer
The process of finding new therapeutic indications for currently used drugs, defined as
'repurposing', is receiving growing attention. Chloroquine and hydroxychloroquine, with an …

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

CA Devaux, JM Rolain, P Colson, D Raoult - International journal of …, 2020 - Elsevier
ABSTRACT Recently, a novel coronavirus (2019-nCoV), officially known as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China. Despite drastic …

Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases

MAA Al‐Bari - Pharmacology research & perspectives, 2017 - Wiley Online Library
Emerging viruses such as HIV, dengue, influenza A, SARS coronavirus, Ebola, and other
viruses pose a significant threat to human health. Majority of these viruses are responsible …

The use of antimalarial drugs against viral infection

S D'Alessandro, D Scaccabarozzi, L Signorini… - Microorganisms, 2020 - mdpi.com
In recent decades, drugs used to treat malaria infection have been shown to be beneficial for
many other diseases, including viral infections. In particular, they have received special …

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

MJ Vincent, E Bergeron, S Benjannet, BR Erickson… - Virology journal, 2005 - Springer
Background Severe acute respiratory syndrome (SARS) is caused by a newly discovered
coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently …

Hydroxychloroquine: from malaria to autoimmunity

I Ben-Zvi, S Kivity, P Langevitz, Y Shoenfeld - Clinical reviews in allergy & …, 2012 - Springer
Quinine was first recognized as a potent antimalarial agent hundreds of years ago. Since
then, the beneficial effects of quinine and its more advanced synthetic forms, chloroquine …

[HTML][HTML] Drug repurposing and human parasitic protozoan diseases

KT Andrews, G Fisher, TS Skinner-Adams - International Journal for …, 2014 - Elsevier
Parasitic diseases have an enormous health, social and economic impact and are a
particular problem in tropical regions of the world. Diseases caused by protozoa and …

Hydroxychloroquine in rheumatic autoimmune disorders and beyond

EL Nirk, F Reggiori, M Mauthe - EMBO molecular medicine, 2020 - embopress.org
Initially used as antimalarial drugs, hydroxychloroquine (HCQ) and, to a lesser extent,
chloroquine (CQ) are currently being used to treat several diseases. Due to its cost …

[HTML][HTML] Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review

AM Hashem, BS Alghamdi, AA Algaissi… - Travel medicine and …, 2020 - Elsevier
Abstract The rapidly spreading Coronavirus Disease (COVID-19) pandemic, caused by the
severe acute respiratory syndrome coronavirus (SARS-CoV-2), represents an …