Zinc signals and immunity

M Maywald, I Wessels, L Rink - International journal of molecular sciences, 2017 - mdpi.com
Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …

Immune dysfunction in patients with diabetes mellitus (DM)

SE Geerlings, AIM Hoepelman - FEMS Immunology & Medical …, 1999 - academic.oup.com
Patients with diabetes mellitus (DM) have infections more often than those without DM. The
course of the infections is also more complicated in this patient group. One of the possible …

[HTML][HTML] A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein

PP Cavicchia, SE Steck, TG Hurley, JR Hussey… - The Journal of …, 2009 - Elsevier
Inflammation is associated with a number of chronic conditions, such as cancer and
cardiovascular disease. Reducing inflammation may help prevent or treat these conditions …

Zinc and the immune system

L Rink - Proceedings of the Nutrition Society, 2000 - cambridge.org
Zn is an essential trace element for all organisms. In human subjects body growth and
development is strictly dependent on Zn. The nervous, reproductive and immune systems …

[HTML][HTML] Zinc-altered immune function

KH Ibs, L Rink - The Journal of nutrition, 2003 - Elsevier
Zinc is known to be essential for all highly proliferating cells in the human body, especially
the immune system. A variety of in vivo and in vitro effects of zinc on immune cells mainly …

[HTML][HTML] Zinc-altered immune function and cytokine production

L Rink, H Kirchner - The Journal of nutrition, 2000 - Elsevier
Although the intriguing role of zinc as an essential trace element for immune function is well
established, particular progress in determining the molecular principles of action of this ion …

Altered cytokine production in the elderly

L Rink, I Cakman, H Kirchner - Mechanisms of ageing and development, 1998 - Elsevier
Elderly persons are more susceptible to bacterial and virus infections and neoplasias than
young adults. This is related to an impaired immune response. Lymphocytes of the elderly …

Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes

H Haase, JL Ober-Blöbaum, G Engelhardt… - The Journal of …, 2008 - journals.aai.org
Cytosolic alterations of calcium ion concentrations are an integral part of signal transduction.
Similar functions have been hypothesized for other metal ions, in particular zinc (Zn 2+), but …

Signal transduction in monocytes: the role of zinc ions

H Haase, L Rink - Biometals, 2007 - Springer
The availability of zinc has a regulatory role in the immune system. It can have either pro-or
anti-inflammatory effects, which both seem to be a consequence of a direct interaction of …

Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-α and IL-1β production in monocytes by elevation of …

V von Bülow, L Rink, H Haase - The Journal of Immunology, 2005 - journals.aai.org
The trace element zinc affects several aspects of immune function, such as the release of
proinflammatory cytokines from monocytes. We investigated the role of cyclic nucleotide …