GDNF/RET signaling in dopamine neurons in vivo

JA Conway, S Ince, S Black, ER Kramer - Cell and tissue research, 2020 - Springer
The glial cell line–derived neurotrophic factor (GDNF) and its canonical receptor Ret can
signal both in tandem and separately to exert many vital functions in the midbrain dopamine …

[HTML][HTML] Chronic 2-fold elevation of endogenous GDNF levels is safe and enhances motor and dopaminergic function in aged mice

G Turconi, J Kopra, V Võikar, N Kulesskaya… - … Therapy Methods & …, 2020 - cell.com
Glial cell line-derived neurotrophic factor (GDNF) supports function and survival of
dopamine neurons that degenerate in Parkinson's disease (PD). Ectopic delivery of GDNF in …

RET isoforms contribute differentially to invasive processes in pancreatic ductal adenocarcinoma

EY Lian, BD Hyndman, S Moodley, SM Maritan… - Oncogene, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a therapeutically challenging disease with
poor survival rates, owing to late diagnosis and early dissemination. These tumors …

RET overexpression leads to increased brain metastatic competency in luminal breast cancer

P Jagust, AM Powell, M Ola, L Watson… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Breast cancer brain metastasis is a rising occurrence, necessitating a better
understanding of the mechanisms involved for effective management. Breast cancer brain …

[图书][B] Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders

HM Mansour, MM Khattab, AS El-Khatib - 2023 - books.google.com
Overexpression of receptor tyrosine kinases (RTKs) has been implicated in cancer.
Increasing evidence suggests that dysregulation of RTKs is reported in many …

[PDF][PDF] GDNF/RET signaling in dopamine neurons in vivo James A. Conway1, Selvi Ince1, Stephanie Black2, Edgar R. Kramer1

JA Conway, S Ince, S Black, ER Kramer - core.ac.uk
The Glial cell-line derived neurotrophic factor (GDNF) and its canonical receptor Ret can
signal both in tandem and separately to exert many vital functions in the midbrain dopamine …