Roles of macrophage polarization and macrophage-derived miRNAs in pulmonary fibrosis

A Kishore, M Petrek - Frontiers in immunology, 2021 - frontiersin.org
This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease …

Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases

MK Skytthe, JH Graversen, SK Moestrup - International journal of …, 2020 - mdpi.com
The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

The role of diverse immune cells in sarcoidosis

H Zhang, U Costabel, H Dai - Frontiers in immunology, 2021 - frontiersin.org
Sarcoidosis is a systemic inflammatory disorder of unknown etiology characterized by tissue
infiltration with macrophages and lymphocytes and associated non-caseating granuloma …

Sarcoidosis as an autoimmune disease

AA Starshinova, AM Malkova, NY Basantsova… - Frontiers in …, 2020 - frontiersin.org
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis
still remain unknown. Most researchers allude to the possible autoimmune or immune …

Sarcoidosis and the mTOR, Rac1, and autophagy triad

Y Pacheco, CX Lim, T Weichhart, D Valeyre… - Trends in …, 2020 - cell.com
Sarcoidosis is an enigmatic multisystem disease characterized by the development and
accumulation of granulomas: a compact collection of macrophages that have differentiated …

Immune mechanisms in fibrotic pulmonary sarcoidosis

P Weeratunga, DR Moller, LP Ho - European Respiratory …, 2022 - Eur Respiratory Soc
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily
mapped out over the past few decades. Despite this, the underpinning mechanisms for …

Metabolic programming of macrophages: implications in the pathogenesis of granulomatous disease

JL Wilson, HK Mayr, T Weichhart - Frontiers in immunology, 2019 - frontiersin.org
Metabolic reprogramming is rapidly gaining appreciation in the etiology of immune cell
dysfunction in a variety of diseases. Tuberculosis, schistosomiasis, and sarcoidosis …

[HTML][HTML] Research on the mechanism of berberine in the treatment of COVID-19 pneumonia pulmonary fibrosis using network pharmacology and molecular docking

J Cao, L Li, L Xiong, C Wang, Y Chen, X Zhang - Phytomedicine Plus, 2022 - Elsevier
Purpose Pulmonary fibrosis caused by COVID-19 pneumonia is a serious complication of
COVID-19 infection, there is a lack of effective treatment methods clinically. This article …

Clinical presentations, pathogenesis, and therapy of sarcoidosis: state of the art

F Polverino, E Balestro, P Spagnolo - Journal of clinical medicine, 2020 - mdpi.com
Sarcoidosis is a systemic disease of unknown etiology characterized by the presence of
noncaseating granulomas that can occur in any organ, most commonly the lungs. Early and …

Prognostic biomarkers of sarcoidosis: a comparative study of serum chitotriosidase, ACE, lysozyme, and KL‐6

L Bergantini, F Bianchi, P Cameli, MA Mazzei… - Disease …, 2019 - Wiley Online Library
Purpose. Sarcoidosis is a systemic granulomatous disease with unknown etiology. Many
clinical presentations have been reported, and acute disease needs to be distinguished …