Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

Hybrid semiconductor–metal nanoparticles (HNPs) manifest unique combined and often
synergetic properties stemming from the materials combination. These structures exhibit …

Background Thyroid cancer is one of the most prevalent malignancies in endocrine system.
Further understanding and revealing the molecular mechanism underlying thyroid cancer …

Abstract Thyroid hormones (TH) 3, 5, 3′, 5'-tetraiodothyronine or thyroxine (T4) and 3, 5, 3'-
triiodothyronine (T3) contain iodine atoms as part of their structure, and their synthesis occur …

Whole genome sequencing approaches have provided unprecedented insights into the
genetic lesions responsible for the onset, progression and dedifferentiation of various types …

Significance: Among the NADPH oxidases, the dual oxidases, DUOX1 and DUOX2,
constitute a distinct subfamily initially called thyroid oxidases, based on their high level of …

In the past few decades, there has been a lot of interest in plant constituents for their
antioxidant, anti-inflammatory, anti-microbial and anti-proliferative properties. However …

Background Sodium/iodide symporter (NIS)-mediated iodide uptake plays an important
physiological role in regulating thyroid gland function, as well as in diagnosing and treating …

Simple Summary Increased oxidative stress (OS) has been implicated as a relevant risk
factor for cancer development and progression. The incidence of differentiated thyroid …

Thyronamines (3-T1AM, T0AM) are endogenous compounds probably derived from L-
thyroxine or its intermediate metabolites. Combined activities of intestinal deiodinases and …