Genetics of migraine: where are we now?
L Grangeon, KS Lange, M Waliszewska-Prosół… - The Journal of …, 2023 - Springer
Migraine is a complex brain disorder explained by the interaction of genetic and
environmental factors. In monogenic migraines, including familial hemiplegic migraine and …
environmental factors. In monogenic migraines, including familial hemiplegic migraine and …
Using Mendelian randomization analysis to better understand the relationship between mental health and substance use: a systematic review
JL Treur, MR Munafò, E Logtenberg… - Psychological …, 2021 - cambridge.org
BackgroundPoor mental health has consistently been associated with substance use
(smoking, alcohol drinking, cannabis use, and consumption of caffeinated drinks). To …
(smoking, alcohol drinking, cannabis use, and consumption of caffeinated drinks). To …
Systematic review of Mendelian randomization studies on risk of cancer
G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …
(MR) literature on cancer risk and to identify associations supported by robust evidence …
Migraine genetics: Status and road forward
AVE Harder, GM Terwindt, DR Nyholt… - …, 2023 - journals.sagepub.com
Background Migraine is considered a multifactorial genetic disorder. Different platforms and
methods are used to unravel the genetic basis of migraine. Initially, linkage analysis in …
methods are used to unravel the genetic basis of migraine. Initially, linkage analysis in …
Ancestry: How researchers use it and what they mean by it
Background: Ancestry is often viewed as a more objective and less objectionable population
descriptor than race or ethnicity. Perhaps reflecting this, usage of the term “ancestry” is …
descriptor than race or ethnicity. Perhaps reflecting this, usage of the term “ancestry” is …
Associations between indicators of socioeconomic position and DNA methylation: a scoping review
Background Socioeconomic position (SEP) is a major determinant of health across the life
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
Long-term cost-effectiveness of interventions for obesity: A mendelian randomisation study
Background The prevalence of obesity has increased in the United Kingdom, and reliably
measuring the impact on quality of life and the total healthcare cost from obesity is key to …
measuring the impact on quality of life and the total healthcare cost from obesity is key to …
Effects of depression on employment and social outcomes: a Mendelian randomisation study
Background Depression is associated with socioeconomic disadvantage. However, whether
and how depression exerts a causal effect on employment remains unclear. We used …
and how depression exerts a causal effect on employment remains unclear. We used …
Dissecting the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases: insights from bidirectional …
X Zheng, Y Yang, J Chen, B Lu - BMC Public Health, 2023 - Springer
Objectives Observational studies have revealed that socioeconomic status is associated
with cardiovascular health. However, the potential causal effect remains unclear. Hence, we …
with cardiovascular health. However, the potential causal effect remains unclear. Hence, we …
A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach
In this study we examine the instrument selection strategies currently used throughout the
type 2 diabetes and HbA1c Mendelian randomization (MR) literature. We then argue for a …
type 2 diabetes and HbA1c Mendelian randomization (MR) literature. We then argue for a …