Macrophages have important roles in immune surveillance and in the maintenance of
kidney homeostasis; their response to renal injury varies enormously depending on the …

Fibrotic disorders of the renal, pulmonary, cardiac, and hepatic systems are associated with
significant morbidity and mortality. Effective therapies to prevent or curtail the advancement …

Senescence, a persistent form of cell-cycle arrest, is often associated with a diverse
secretome, which provides complex functionality for senescent cells within the tissue …

Circular RNAs (circRNAs) represent a new type of regulatory noncoding RNA that only
recently has been identified and cataloged. Emerging evidence indicates that circRNAs …

Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes
and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or …

Lipoxins, which are endogenously produced lipid mediators, promote the resolution of
inflammation, and may inhibit fibrosis, suggesting a possible role in modulating renal …

Type 2 diabetes mellitus (T2DM) is a global public health problem of epidemic proportions,
with 60–70% of affected individuals suffering from associated neurovascular complications …

The retina is one of the most energy-demanding tissues in the human body. Photoreceptors
in the outer retina rely on nutrient support from the neighboring retinal pigment epithelium …

Background Diabetic nephropathy (DN) is the most common cause of end-stage renal
disease, affecting∼ 30% of the rapidly growing diabetic population, and strongly associated …

Objectives Transforming growth factor β1 (TGF‐β1), an essential cytokine belongs to TGF‐β
superfamily, is crucial for female fertility. Increasing evidence show that long noncoding …