[HTML][HTML] The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation
Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …
[HTML][HTML] The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
[HTML][HTML] The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
The multifunctional nucleocapsid (N) protein in SARS-CoV-2 binds the~ 30 kb viral RNA
genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein …
genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein …
Architecture and self‐assembly of the SARS‐CoV‐2 nucleocapsid protein
Q Ye, AMV West, S Silletti, KD Corbett - Protein Science, 2020 - Wiley Online Library
The COVID‐2019 pandemic is the most severe acute public health threat of the twenty‐first
century. To properly address this crisis with both robust testing and novel treatments, we …
century. To properly address this crisis with both robust testing and novel treatments, we …
[HTML][HTML] The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
[HTML][HTML] The coronavirus nucleocapsid is a multifunctional protein
R McBride, M Van Zyl, BC Fielding - Viruses, 2014 - mdpi.com
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic
RNA, interacts with the viral membrane protein during virion assembly and plays a critical …
RNA, interacts with the viral membrane protein during virion assembly and plays a critical …
The severe acute respiratory syndrome coronavirus nucleocapsid inhibits type I interferon production by interfering with TRIM25-mediated RIG-I ubiquitination
Y Hu, W Li, T Gao, Y Cui, Y Jin, P Li, Q Ma… - Journal of …, 2017 - Am Soc Microbiol
Severe acute respiratory syndrome (SARS) is a respiratory disease, caused by a
coronavirus (SARS-CoV), that is characterized by atypical pneumonia. The nucleocapsid …
coronavirus (SARS-CoV), that is characterized by atypical pneumonia. The nucleocapsid …
The SARS coronavirus nucleocapsid protein–forms and functions
C Chang, MH Hou, CF Chang, CD Hsiao, T Huang - Antiviral research, 2014 - Elsevier
The nucleocapsid phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy
BW Neuman, BD Adair, C Yoshioka, JD Quispe… - Journal of …, 2006 - Am Soc Microbiol
Coronavirus particles are enveloped and pleomorphic and are thus refractory to
crystallization and symmetry-assisted reconstruction. A novel methodology of single-particle …
crystallization and symmetry-assisted reconstruction. A novel methodology of single-particle …
Molecular interactions in the assembly of coronaviruses
CAM de Haan, PJM Rottier - Advances in virus research, 2005 - Elsevier
Publisher Summary This chapter describes the interactions between the different structural
components of the viruses and discusses their relevance for the process of virion formation …
components of the viruses and discusses their relevance for the process of virion formation …