Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …
between cells and their environments and eventually propagate to systemic levels. In the …
Causes and consequences of baseline cerebral blood flow reductions in Alzheimer's disease
Reductions of baseline cerebral blood flow (CBF) of∼ 10–20% are a common symptom of
Alzheimer's disease (AD) that appear early in disease progression and correlate with the …
Alzheimer's disease (AD) that appear early in disease progression and correlate with the …
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB …
N Yan, Z Xu, C Qu, JJ Zhang - International Immunopharmacology, 2021 - Elsevier
Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
Associations between vascular risk factors and brain MRI indices in UK Biobank
Aims Several factors are known to increase risk for cerebrovascular disease and dementia,
but there is limited evidence on associations between multiple vascular risk factors (VRFs) …
but there is limited evidence on associations between multiple vascular risk factors (VRFs) …
Imaging recommendations for acute stroke and transient ischemic attack patients: a joint statement by the American Society of Neuroradiology, the American College …
M Wintermark, PC Sanelli, GW Albers… - American Journal …, 2013 - Am Soc Neuroradiology
Stroke is a leading cause of death and disability worldwide. Imaging plays a critical role in
evaluating patients suspected of acute stroke and transient ischemic attack, especially …
evaluating patients suspected of acute stroke and transient ischemic attack, especially …
Obesity-associated neurodegeneration pattern mimics Alzheimer's disease in an observational cohort study
Background: Excess weight in adulthood leads to health complications such as diabetes,
hypertension, or dyslipidemia. Recently, excess weight has also been related to brain …
hypertension, or dyslipidemia. Recently, excess weight has also been related to brain …
Postischemic inflammation in acute stroke
S Vidale, A Consoli, M Arnaboldi… - Journal of Clinical …, 2017 - synapse.koreamed.org
Cerebral ischemia is caused by arterial occlusion due to a thrombus or an embolus. Such
occlusion induces multiple and concomitant pathophysiological processes that involve …
occlusion induces multiple and concomitant pathophysiological processes that involve …
Atrial fibrillation is associated with reduced brain volume and cognitive function independent of cerebral infarcts
Background and Purpose—Atrial fibrillation (AF) has been associated with cognitive decline
independent of stroke, suggesting additional effects of AF on the brain. We aimed to assess …
independent of stroke, suggesting additional effects of AF on the brain. We aimed to assess …
[HTML][HTML] Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants
N Raz, Y Yang, CL Dahle, S Land - … Acta (BBA)-Molecular Basis of Disease, 2012 - Elsevier
Aging is associated with appearance of white matter hyperintensities (WMH) on MRI scans.
Vascular risk and inflammation, which increase with age, may contribute to white matter …
Vascular risk and inflammation, which increase with age, may contribute to white matter …
Imaging of acute ischemic stroke
Background: Over 80% of strokes result from ischemic damage to the brain due to an acute
reduction in the blood supply. Around 25-35% of strokes present with large vessel occlusion …
reduction in the blood supply. Around 25-35% of strokes present with large vessel occlusion …