Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Herpes simplex virus cell entry mechanisms: an update

K Madavaraju, R Koganti, I Volety… - Frontiers in cellular …, 2021 - frontiersin.org
Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating
infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and …

Herpes simplex epithelial and stromal keratitis: an epidemiologic update

AV Farooq, D Shukla - Survey of ophthalmology, 2012 - Elsevier
Herpes simplex virus (HSV) is associated with a variety of ocular diseases, including
epithelial and stromal keratitis. HSV can cause stromal opacification and is believed to be …

Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry

J Akhtar, D Shukla - The FEBS journal, 2009 - Wiley Online Library
Herpes simplex virus type‐1 and type‐2 are highly prevalent human pathogens causing life‐
long infections. The process of infection begins when the virions bind heparan sulfate …

HSV-1 cytoplasmic envelopment and egress

I Ahmad, DW Wilson - International journal of molecular sciences, 2020 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses

D Rudnicka, J Feldmann, F Porrot, S Wietgrefe… - Journal of …, 2009 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) efficiently propagates through cell-to-cell
contacts, which include virological synapses (VS), filopodia, and nanotubes. Here, we …

Infection and transport of herpes simplex virus type 1 in neurons: role of the cytoskeleton

M Miranda-Saksena, CE Denes, RJ Diefenbach… - Viruses, 2018 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a neuroinvasive human pathogen that has the ability
to infect and replicate within epithelial cells and neurons and establish a life-long latent …

Capturing the start point of the virus–cell interaction with high-speed 3D single-virus tracking

C Johnson, J Exell, Y Lin, J Aguilar, KD Welsher - Nature methods, 2022 - nature.com
The early stages of the virus–cell interaction have long evaded observation by existing
microscopy methods due to the rapid diffusion of virions in the extracellular space and the …

Bridging the gap: virus long-distance spread via tunneling nanotubes

RJJ Jansens, A Tishchenko, HW Favoreel - Journal of virology, 2020 - Am Soc Microbiol
Tunneling nanotubes (TNTs) are actin-based intercellular conduits that connect distant cells
and allow intercellular transfer of molecular information, including genetic information …

Exploitation of cytoskeletal networks during early viral infection

D Walsh, MH Naghavi - Trends in microbiology, 2019 - cell.com
Being dependent upon host transport systems to navigate the cytoplasm, viruses have
evolved various strategies to manipulate cytoskeletal functions. Generally, viruses use the …