Diseases and molecular diagnostics: a step closer to precision medicine

S Dwivedi, P Purohit, R Misra, P Pareek, A Goel… - Indian Journal of Clinical …, 2017 - Springer
The current advent of molecular technologies together with a multidisciplinary interplay of
several fields led to the development of genomics, which concentrates on the detection of …

Relationship between cigarette use and prostate cancer risk: what do we know and what should we do?

JI Nolazco, LA Mucci, R Sosnowski… - Prostate Cancer and …, 2023 - nature.com
Prostate cancer is the second most commonly diagnosed cancer and the fifth leading cause
of cancer death among men worldwide, with an estimated 1,414,000 new cancer cases and …

[HTML][HTML] Lifestyle habits to prevent the development of benign prostatic hyperplasia: analysis of Japanese nationwide datasets

Y Nagakura, M Hayashi, S Kajioka - Prostate international, 2022 - Elsevier
Objectives Benign prostatic hyperplasia (BPH) refers to nonmalignant hyperplasia of
prostate tissue, which causes lower urinary tract symptoms and has become a global public …

[HTML][HTML] Chronic prostatitis and chronic pelvic pain syndrome in men

H Pendegast, S Leslie, D Rosario - StatPearls, 2024 - statpearls.com
Symptomatic inflammatory conditions of the prostate are quite common, accounting for about
2 million outpatient visits annually in the United States.[1] These visits are evenly split …

[HTML][HTML] Smoking: Its impact on urologic health

D Mobley, N Baum - Reviews in urology, 2015 - ncbi.nlm.nih.gov
Tobacco use remains the single largest preventable cause of disease and premature death
in the United States, and smoking is a leading cause of cancer and death from cancer. There …

Impact of interleukin-18 polymorphisms-607A/C and-137G/C on oral cancer occurrence and clinical progression

HT Tsai, CH Hsin, YH Hsieh, CH Tang, SF Yang… - PloS one, 2013 - journals.plos.org
Background The purpose of this study was to identify gene polymorphisms of interleukin-18
(IL-18)-607A/C and-137G/C specific to patients with oral cancer susceptibility and …

[HTML][HTML] Genotoxic and carcinogenic effect of gutkha: a fast-growing smokeless tobacco

B Sankhla, K Kachhwaha, SY Hussain… - Addiction & …, 2018 - ncbi.nlm.nih.gov
Oral cancer is a highly lethal disease and one of the most debilitating and disfiguring of all
malignancies in the world. According to Global Adult Tobacco Survey (GATS) 2010 report …

Genetic variability at promoters of IL-18 (pro-) and IL-10 (anti-) inflammatory gene affects susceptibility and their circulating serum levels: an explorative study of …

S Dwivedi, A Goel, S Khattri, A Mandhani, P Sharma… - Cytokine, 2015 - Elsevier
Inflammation is an important hallmark of all types of cancers with a well-established role in
carcinogenesis. The net inflammatory response is determined by the balance between pro …

PACAP protects against ethanol and nicotine toxicity in SH-SY5Y cells: Implications for drinking-smoking co-morbidity

S Manavalan, B Getachew, KF Manaye… - Neurotoxicity …, 2017 - Springer
The detrimental effects of heavy drinking and smoking are multiplied when the two are
combined. Treatment modalities for each and especially for the combination are very limited …

[HTML][HTML] Association between IL-18-607 C/A polymorphism and the risk of prostate cancer: a meta-analysis of case-control studies

G Yuanyuan, Y Xue, L Yachao, F Xiao… - Asian Pacific Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Accumulating evidence shows that cytokines play an important role in the
proliferation of prostate cancer. This research is trying to determine that IL-18-607 C/A …