Sequence symmetry analysis (SSA) is a method for detecting adverse drug events by
utilizing computerized claims data. The method has been increasingly used to investigate …

Background The (prescription) sequence symmetry analysis (PSSA) design has been used
to identify potential prescribing cascade signals by assessing the prescribing sequence of …

Abstract Background and Objective. Explainable Artificial Intelligence (XAI) has been
identified as a viable method for determining the importance of features when making …

Abstract Introduction The Janus kinase (JAK) inhibitors tofacitinib and baricitinib are new
treatments for rheumatic diseases. Recent concerns regarding the risk of thrombosis have …

The misattribution of an adverse drug reaction (ADR) as a symptom or illness can lead to the
prescribing of additional medication, referred to as a prescribing cascade. The aim of this …

Introduction The prevalence of polymorphisms among the metabolising enzymes and
pharmacodynamic receptors relevant for the thiazolidinediones differs by ethnic group, a …

Pharmacovigilance is defined by the World Health Organization as “the science and
activities relating to the detection, assessment, understanding and prevention of adverse …

Abstract Purpose The US Food and Drug Administration Adverse Event Reporting System
(FAERS), one of the world's largest spontaneous reporting systems, is difficult to use …

Abstract Motivation Adverse drug reactions (ADRs) are one of the leading causes of
morbidity and mortality and thus should be detected early to reduce consequences on …

Abstract Background Chronic Obstructive Pulmonary Disease is characterised by declining
lung function and a greater oxidative stress burden due to reduced activity of antioxidant …