Determination of haplotype phase is becoming increasingly important as we enter the era of
large-scale sequencing because many of its applications, such as imputing low-frequency …

Abstract DNA methyltransferase 3β (DNMT3B) is a gene encoding a de novo methylation
enzyme that is required for DNA methylation during mammalian embryo development …

Introduction The renin–angiotensin–aldosterone system (RAAS), a metabolic cascade
regulating pressure and circulating blood volume, has been considered the main system …

The human dopamine transporter gene SLC6A3 has been consistently implicated in several
neuropsychiatric diseases but the disease mechanism remains elusive. In this risk synthesis …

Abstract Angiotensin-converting enzyme 2 (ACE2) plays an important role in the
development of essential hypertension (EH). The aim of this study was to investigate the …

A previous whole-genome association analysis identified lysine demethylase 6A (KDM6A),
which encodes a type of histone demethylase, as a candidate gene associated to goat …

Abstract Growth differentiation factor 9 (GDF9) gene is an effective intra-ovarian regulator; it
plays a crucial role in early folliculogenesis in female mammals. The non synonymous …

The down syndrome cell adhesion molecule like 1 (DSCAML1), is associated with the
development of the nervous system and neurologic diseases. Previous Genome-wide …

Primary Sjogren's syndrome (pSS) is complicated by B-cell lymphoma in 5–10% of patients.
Several clinical and serological features are proposed as adverse predictors for such …

Currently, algorithms and softwares for genetic analysis of diploid organisms with bi-allelic
markers are well-established, while those for polyploids are limited. Here, we present …