Junctional adhesion molecules (JAMs) are immunoglobulin superfamily (IgSF) proteins
expressed at cell junctions in epithelial and endothelial cells as well as on the surface of …

Apical–basal polarity and a highly organized actin cytoskeleton are main characteristics of
epithelial cells that support exchange of ions and nutrients from one body compartment to …

Mucosal surfaces are lined by epithelial cells that form a physical barrier protecting the body
against external noxious substances and pathogens. At a molecular level, the mucosal …

The intestinal epithelium forms the boundary between the intestinal immune system in the
lamina propria and the outside world, the intestinal lumen, which contains a diverse array of …

Background & Aims Crohn's disease is a highly heterogeneous inflammatory bowel disease
comprising multiple clinical phenotypes. Genome-wide association studies (GWASs) have …

The intestinal barrier plays a critical role in humans in the transport of nutrients and
macromolecules. At the same time, it has to provide an effective barrier to harmful …

Junctional adhesion molecule (JAM)-A is an integral membrane protein at tight junctions of
epithelial cells which associates with the cell polarity protein PAR-3. Here, we demonstrate …

Junctional adhesion molecules (JAMs) are cell-cell adhesion molecules of the
immunoglobulin superfamily and are involved in the regulation of diverse atherosclerosis …

MAGUK with inverted domain structure-1 (MAGI-1) is a membrane-associated protein with
one guanylate kinase, six PSD-95/Dlg-A/ZO-1 (PDZ), and two WW domains and is localized …

Abstract Junctional adhesion molecule 4 (JAM4) is a cell adhesion molecule that interacts
with a tight junction protein, membrane-associated guanylate kinase inverted 1 (MAGI-1) …