Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …

Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …

Messenger RNA (mRNA) holds great potential in developing immunotherapy, protein
replacement, and genome editing. In general, mRNA does not have the risk of being …

The genetic material within cells plays a pivotal role in shaping the structure and function of
living organisms. Manipulating an organism's genome to correct inherited abnormalities or …

In the last decade, messenger ribonucleic acid (mRNA)-based drugs have gained great
interest in both immunotherapy and non-immunogenic applications. This surge in interest …

The use of mRNA and ribonucleoproteins (RNPs) as therapeutic agents is a promising
strategy for treating diseases like cancer and infectious diseases. This review provides …

RNA-based therapeutics have emerged as promising approaches to modulate gene
expression and generate therapeutic proteins or antigens capable of inducing immune …

Virus-like particles (VLPs) have natural structural antigens similar to those found in viruses,
making them valuable in vaccine immunization. Furthermore, VLPs have demonstrated …

Rare genetic diseases, often referred to as orphan diseases due to their low prevalence and
limited treatment options, have long posed significant challenges to our medical system. In …