Multivalent glycosystems for human lectins

M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …

Glyco-gold nanoparticles: synthesis and applications

F Compostella, O Pitirollo, A Silvestri… - Beilstein journal of …, 2017 - beilstein-journals.org
Glyco-gold nanoparticles combine in a single entity the peculiar properties of gold
nanoparticles with the biological activity of carbohydrates. The result is an exciting …

Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus

Q Zhu, Z Shen, F Chiodo, S Nicolardi… - Nature …, 2020 - nature.com
Glycans are involved in various life processes and represent critical targets of biomedical
developments. Nevertheless, the accessibility to long glycans with precise structures …

Preparation and immunogenicity of gold glyco-nanoparticles as antipneumococcal vaccine model

M Vetro, D Safari, S Fallarini, K Salsabila… - …, 2017 - Taylor & Francis
Aim: Nanotechnology-based fully synthetic carbohydrate vaccines are promising
alternatives to classic polysaccharide/protein conjugate vaccines. We have prepared gold …

Effective targeting of DC-sign by α-fucosylamide functionalized gold nanoparticles

D Arosio, F Chiodo, JJ Reina, M Marelli… - Bioconjugate …, 2014 - ACS Publications
Dendritic Cells (DCs), the most potent antigen-presenting cells, play a critical role in the
detection of invading pathogens, which are recognized also by multiple carbohydrate …

[HTML][HTML] Glycosystems in nanotechnology: Gold glyconanoparticles as carrier for anti-HIV prodrugs

F Chiodo, M Marradi, J Calvo, E Yuste… - Beilstein Journal of …, 2014 - beilstein-journals.org
The therapeutic approach for the treatment of HIV infection is based on the highly active
antiretroviral therapy (HAART), a cocktail of antiretroviral drugs. Notwithstanding HAART has …

Galactofuranose-coated gold nanoparticles elicit a pro-inflammatory response in human monocyte-derived dendritic cells and are recognized by DC-SIGN

F Chiodo, M Marradi, J Park, AFJ Ram… - ACS chemical …, 2014 - ACS Publications
Galactofuranose (Gal f) is the five-membered ring form of galactose exclusively found in
nonmammalian species, among which several are pathogens. To determine the putative …

Complementation of ELISA and an interdigitated electrode surface in gold nanoparticle functionalization for effective detection of human blood clotting defects

S Guo, T Lakshmipriya, SCB Gopinath, P Anbu… - Nanoscale Research …, 2019 - Springer
Developing an enhanced diagnosis using biosensors is important for the treatment of
patients before disease complications arise. Improving biosensors would enable the …

Simple engineering of hybrid cellulose nanocrystal–gold nanoparticles results in a functional glyconanomaterial with biomolecular recognition properties

G Biagiotti, G Toniolo, M Albino, M Severi… - Nanoscale …, 2023 - pubs.rsc.org
Cellulose nanocrystal and gold nanoparticles are assembled, in a unique way, to yield a
novel modular glyconanomaterial whose surface is then easily engineered with one or two …

Negatively charged glyconanoparticles modulate and stabilize the secondary structures of a gp120 V3 loop peptide: Toward fully synthetic HIV vaccine candidates

PD Gianvincenzo, J Calvo, S Perez… - Bioconjugate …, 2015 - ACS Publications
The third variable region (V3 peptide) of the HIV-1 gp120 is a major immunogenic domain of
HIV-1. Controlling the formation of the immunologically active conformation is a crucial step …