Genetic Encoding of Phosphorylated Amino Acids into Proteins

MC Allen, PA Karplus, RA Mehl, RB Cooley - Chemical Reviews, 2024 - ACS Publications
Reversible phosphorylation is a fundamental mechanism for controlling protein function.
Despite the critical roles phosphorylated proteins play in physiology and disease, our ability …

Kinetochore and ionomic adaptation to whole-genome duplication in Cochlearia shows evolutionary convergence in three autopolyploids

SM Bray, T Hämälä, M Zhou, S Busoms, S Fischer… - Cell Reports, 2024 - cell.com
Whole-genome duplication (WGD) occurs in all kingdoms and impacts speciation,
domestication, and cancer outcome. However, doubled DNA management can be …

Pauli Exclusion by n→ π* Interactions: Implications for Paleobiology

J Yang, V Kojasoy, GJ Porter, RT Raines - ACS Central Science, 2024 - ACS Publications
Proteins have evolved to function in an aqueous environment. Collagen, which provides the
bodily scaffold for animals, has a special need to retain its integrity. This need was …

A genomic toolkit for winged bean Psophocarpus tetragonolobus

WK Ho, AS Tanzi, F Sang, N Tsoutsoura… - Nature …, 2024 - nature.com
A sustainable supply of plant protein is critical for future generations and needs to be
achieved while reducing green house gas emissions from agriculture and increasing …

4,4-Difluoroproline as a Unique 19F NMR Probe of Proline Conformation

HK Ganguly, BA Ludwig, CM Tressler, MR Bhatt… - Biochemistry, 2024 - ACS Publications
Despite the importance of proline conformational equilibria (trans versus cis amide and exo
versus endo ring pucker) on protein structure and function, there is a lack of convenient …

Helical twists and β‐turns in structures at serine–proline sequences: Stabilization of cis‐proline and type VI β‐turns via C–H/O interactions

HC Oven, GPA Yap, NJ Zondlo - Proteins: Structure, Function …, 2024 - Wiley Online Library
Structures at serine‐proline sites in proteins were analyzed using a combination of peptide
synthesis with structural methods and bioinformatics analysis of the PDB. Dipeptides were …

A genomic toolkit for winged bean Psophocarpus tetragonolobus

W Kuan Ho, A Stefano Tanzi… - Nature …, 2024 - nottingham-repository.worktribe.com
A sustainable supply of plant protein is critical for future generations and needs to be
achieved while reducing green house gas emissions from agriculture and increasing …

Effects of phosphorylation on protein backbone dynamics and conformational preferences

D Bickel, W Vranken - Journal of Chemical Theory and …, 2024 - ACS Publications
Phosphorylations are the most common and extensively studied post-translational
modification (PTM) of proteins in eukaryotes. They constitute a major regulatory mechanism …

Kinetochore and ionomic adaptation to whole genome duplication

SM Bray, T Hämälä, M Zhou, S Busoms, S Fischer… - BioRxiv, 2023 - biorxiv.org
Transforming genomic and cellular landscapes in a single generation, whole genome
duplication (WGD) brings fundamental challenges, but is also associated with diversification …

Virtual screening of Ginsenosides for COX-2 inhibition: Insights from in silico docking studies

C Khare, S Jain, H Prajapati, N Dubey… - 2024 - nopr.niscpr.res.in
Analgesic discovery has been a significant aspect to medical practice as they are critical
tools in the management of pain and enhancement of procedures. Nonetheless, the side …