mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …

Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …

Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …

Solid-state is the preferred choice for storage of protein therapeutics to improve stability and
preserve the biological activity by decreasing the physical and chemical degradation …

Introduction Since the coronavirus disease 2019 (COVID-19) pandemic, the value of mRNA
vaccine has been widely recognized worldwide. Messenger RNA (mRNA) therapy platform …

Bacterial conjunctivitis is a worldwide problem that, if untreated, can lead to severe
complications, such as visual impairment and blindness. Topical administration of …

Protein-based therapeutics have revolutionized the pharmaceutical industry and become
vital components in the development of future therapeutics. They offer several advantages …

Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

Background Process intensification is a major hurdle in pharmaceutical process scale-up.
Solvent removal strategies have limited the effectiveness of the overall stability of …

Many biologic drug products, particularly monoclonal antibodies (mAbs), were off-patented
between 2015 and 2020, and this process is continuing as the number of biologics …