Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection
Emergence of SARS‐CoV‐2 variants warrants sustainable efforts to upgrade both the
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
diagnostic and therapeutic protocols. Understanding the details of cellular and molecular …
How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activity
GD Grass, BP Toole - Bioscience Reports, 2016 - portlandpress.com
Matrix metalloproteinases (MMPs) comprise a family of 23 zinc-dependent enzymes
involved in various pathologic and physiologic processes. In cancer, MMPs contribute to …
involved in various pathologic and physiologic processes. In cancer, MMPs contribute to …
Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR …
Activation of the mechanistic target of rapamycin (mTOR) is a key metabolic checkpoint of
pro-inflammatory T-cell development that contributes to the pathogenesis of autoimmune …
pro-inflammatory T-cell development that contributes to the pathogenesis of autoimmune …
Rab35 GTPase: a central regulator of phosphoinositides and F‐actin in endocytic recycling and beyond
K Klinkert, A Echard - Traffic, 2016 - Wiley Online Library
Rab35 is one of the first discovered members of the large Rab GTPase family, yet it received
little attention for 10 years being considered merely as a Rab1‐like GTPase. In 2006, Rab35 …
little attention for 10 years being considered merely as a Rab1‐like GTPase. In 2006, Rab35 …
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166
While several clathrin-independent endocytic processes have been described so far, their
biological relevance often remains elusive, especially in pathophysiological contexts such …
biological relevance often remains elusive, especially in pathophysiological contexts such …
The small GTPase Arf6: an overview of its mechanisms of action and of its role in host–pathogen interactions and innate immunity
T Van Acker, J Tavernier, F Peelman - International journal of molecular …, 2019 - mdpi.com
The small GTase Arf6 has several important functions in intracellular vesicular trafficking and
regulates the recycling of different types of cargo internalized via clathrin-dependent or …
regulates the recycling of different types of cargo internalized via clathrin-dependent or …
Intracellular Membrane Transport in Vascular Endothelial Cells
The main component of blood and lymphatic vessels is the endothelium covering their
luminal surface. It plays a significant role in many cardiovascular diseases. Tremendous …
luminal surface. It plays a significant role in many cardiovascular diseases. Tremendous …
Endocytic recycling of MHC class I molecules in non-professional antigen presenting and dendritic cells
S Montealegre, PM Van Endert - Frontiers in immunology, 2019 - frontiersin.org
Major histocompatibility complex class I (MHC I) molecules are glycoproteins that display
peptide epitopes at the cell surface of nucleated cells for recognition by CD8+ T cells. Like …
peptide epitopes at the cell surface of nucleated cells for recognition by CD8+ T cells. Like …
Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors
Recycling endosomes are stations that sort endocytic cargoes to their appropriate
destinations. Tubular endosomes have been characterized as a recycling endosomal …
destinations. Tubular endosomes have been characterized as a recycling endosomal …
Rab35 GTPase triggers switch-like recruitment of the lowe syndrome lipid phosphatase OCRL on newborn endosomes
C Cauvin, M Rosendale, N Gupta-Rossi, M Rocancourt… - Current Biology, 2016 - cell.com
Phosphoinositide (PtdIns) homeostasis requires a tight spatial and temporal regulation
during the endocytic process [1]. Indeed, PtdIns (4, 5) P 2 plays a crucial role in endocytosis …
during the endocytic process [1]. Indeed, PtdIns (4, 5) P 2 plays a crucial role in endocytosis …